Detalles de la búsqueda
1.
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis.
Hepatology
; 77(4): 1228-1240, 2023 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35993369
2.
Preclinical targeting of liver fibrosis with a 89Zr-labeled Fibrobody® directed against platelet derived growth factor receptor-ß.
Eur J Nucl Med Mol Imaging
; 2024 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38888612
3.
An Efficient Conjugation Approach for Coupling Drugs to Native Antibodies via the PtII Linker Lx for Improved Manufacturability of Antibody-Drug Conjugates.
Angew Chem Int Ed Engl
; 60(6): 3008-3015, 2021 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33185916
4.
Optimization of viral protein ratios for production of rAAV serotype 5 in the baculovirus system.
Gene Ther
; 25(6): 415-424, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30069004
5.
Combined inhibition of bile salt synthesis and intestinal uptake reduces cholestatic liver damage and colonic bile salts in mice.
JHEP Rep
; 6(1): 100917, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38074508
6.
Donor T cells administered over HLA class II barriers mediate antitumor immunity without broad off-target toxicity in a NOD/scid mouse model of acute leukemia.
Biol Blood Marrow Transplant
; 19(6): 867-75, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23500532
7.
IL-7 receptor expression identifies suicide gene-modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors.
Blood
; 117(24): 6469-78, 2011 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-21531977
8.
The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells.
PLoS One
; 18(1): e0270288, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36719899
9.
A mechanistic rationale for combining alemtuzumab and rituximab in the treatment of ALL.
Blood
; 116(26): 5930-40, 2010 Dec 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-20844239
10.
Enhanced Factor IX Activity following Administration of AAV5-R338L "Padua" Factor IX versus AAV5 WT Human Factor IX in NHPs.
Mol Ther Methods Clin Dev
; 15: 221-231, 2019 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31709273
11.
Therapeutic hFIX Activity Achieved after Single AAV5-hFIX Treatment in Hemophilia B Patients and NHPs with Pre-existing Anti-AAV5 NABs.
Mol Ther Methods Clin Dev
; 14: 27-36, 2019 Sep 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31276009
12.
First platinum(II)-based metal-organic linker technology (Lx®) for a plug-and-play development of antibody-drug conjugates (ADCs).
Expert Opin Drug Deliv
; 16(8): 783-793, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31327255
13.
Early detection and rapid isolation of leukemia-reactive donor T cells for adoptive transfer using the IFN-gamma secretion assay.
Clin Cancer Res
; 13(2 Pt 1): 636-43, 2007 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17255287
14.
Limited antitumor-effect associated with toxicity of the experimental cytotoxic drug cyclopentenyl cytosine in NOD/scid mice with acute lymphoblastic leukemia.
Leuk Res
; 31(11): 1545-51, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17459472
15.
Complement-dependent cytotoxicity induced by therapeutic antibodies in B-cell acute lymphoblastic leukemia is dictated by target antigen expression levels and augmented by loss of membrane-bound complement inhibitors.
Leuk Lymphoma
; 58(9): 1-14, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28140725
16.
Responses to donor lymphocyte infusion for acute lymphoblastic leukemia may be determined by both qualitative and quantitative limitations of antileukemic T-cell responses as observed in an animal model for human leukemia.
Exp Hematol
; 33(10): 1172-81, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16219539
17.
Differential effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway in acute lymphoblastic leukemia.
PLoS One
; 8(11): e80070, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24244612
18.
Imatinib mesylate at therapeutic doses has no impact on folliculogenesis or spermatogenesis in a leukaemic mouse model.
Leuk Res
; 36(3): 271-4, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22018447
19.
Long-term culture of primary human lymphoblastic leukemia cells in the absence of serum or hematopoietic growth factors.
Exp Hematol
; 37(3): 376-85, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19135770
20.
Establishment and cytogenetic characterization of a human acute lymphoblastic leukemia cell line (ALL-VG) with ETV6/ABL1 rearrangement.
Cancer Genet Cytogenet
; 185(1): 37-42, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18656692