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1.
Effect of water solvation on the lipophilicity of isomeric pyrimidine-carboxamides.
Bioorg Med Chem
; 23(13): 3408-13, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25963824
2.
Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR.
Bioorg Med Chem Lett
; 22(15): 5098-103, 2012 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22749419
3.
Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.
J Med Chem
; 64(13): 9056-9077, 2021 07 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34110834
4.
Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor.
Cancer Cell
; 39(10): 1404-1421.e11, 2021 10 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34520734
5.
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.
Bioorg Med Chem Lett
; 20(20): 6096-9, 2010 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20817449
6.
5-Bromo-1H-thieno[2,3-d]imidazole.
Acta Crystallogr Sect E Struct Rep Online
; 66(Pt 8): o2021, 2010 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21588332
7.
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1.
Mol Cancer Ther
; 7(8): 2394-404, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18723486
8.
Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.
J Med Chem
; 61(15): 6779-6800, 2018 08 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29944371
9.
Structure-based design and synthesis of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2',4'-diols as novel and potent human CHK1 inhibitors.
J Med Chem
; 50(22): 5253-6, 2007 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17887663
10.
Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors.
J Med Chem
; 59(18): 8306-25, 2016 Sep 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27512831
11.
Optimization of potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitors of heat shock protein 90. Identification of development candidate 2-amino-4-{4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl}-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide.
J Med Chem
; 54(9): 3368-85, 2011 May 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-21438541
12.
Correction to Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors.
J Med Chem
; 59(24): 11196, 2016 12 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27936698
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