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1.
Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid: A proof-of-concept study.
Hepatology
; 64(1): 189-99, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-26597786
2.
CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab.
Eur Respir J
; 46(6): 1740-50, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26493793
3.
Unexpected Toxicology Findings in Rats Dosed With an Antihuman IL-13 Monoclonal Antibody.
Int J Toxicol
; 34(5): 393-407, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26124191
4.
Safety, tolerability and pharmacokinetics of a human anti-interleukin-13 monoclonal antibody (CNTO 5825) in an ascending single-dose first-in-human study.
Br J Clin Pharmacol
; 75(5): 1289-98, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23043368
5.
Pharmacokinetics, Pharmacodynamics, Immunogenicity, Safety, and Tolerability of JNJ-61178104, a Novel Tumor Necrosis Factor-Alpha and Interleukin-17A Bispecific Antibody, in Healthy Subjects.
J Clin Pharmacol
; 59(7): 968-978, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30776134
6.
Galeterone and The Next Generation Galeterone Analogs, VNPP414 and VNPP433-3ß Exert Potent Therapeutic Effects in Castration-/Drug-Resistant Prostate Cancer Preclinical Models In Vitro and In Vivo.
Cancers (Basel)
; 11(11)2019 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31653008
7.
Modification of the Fc Region of a Human Anti-oncostatin M Monoclonal Antibody for Higher Affinity to FcRn Receptor and Extension of Half-life in Cynomolgus Monkeys.
Basic Clin Pharmacol Toxicol
; 121(1): 13-21, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-28132416
8.
Pharmacokinetics and Safety of Single Intravenous Doses of JNJ-54452840, an Anti-ß1-Adrenergic Receptor Antibody Cyclopeptide, in Healthy Male Japanese and Caucasian Participants.
Clin Pharmacokinet
; 55(2): 225-36, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26242382
9.
Non-Clinical Pharmacokinetics, Prediction of Human Pharmacokinetics and First-in-Human Dose Selection for CNTO 5825, an Anti-Interleukin-13 Monoclonal Antibody.
Basic Clin Pharmacol Toxicol
; 117(4): 219-25, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25683750
10.
Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model.
J Steroid Biochem Mol Biol
; 92(3): 155-65, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15555909
11.
Pharmacokinetics of novel inhibitors of androgen synthesis after intravenous administration in mice.
Cancer Chemother Pharmacol
; 51(6): 519-24, 2003 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12715204
12.
Involvement of cytochrome P450 and the flavin-containing monooxygenase(s) in the sulphoxidation of simple sulphides in human liver microsomes.
Life Sci
; 73(3): 359-69, 2003 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-12757843
13.
HPLC analysis of 4-chlorophenyl methyl sulphide and diphenyl sulphide and their corresponding sulphoxides and sulphones in rat liver microsomes.
J Pharm Biomed Anal
; 27(1-2): 315-25, 2002 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11682239
14.
Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.
Biomed Chromatogr
; 19(1): 87-98, 2005 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-15470701
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