Detalles de la búsqueda
1.
Identification of Leishmania donovani PEX5-PTS1 Interaction Inhibitors through Fluorescence Polarization-Based High-Throughput Screening.
Molecules
; 29(8)2024 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38675653
2.
Repurposing of conformationally-restricted cyclopentane-based AKT-inhibitors leads to discovery of potential and more selective antileishmanial agents than miltefosine.
Bioorg Chem
; 141: 106890, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37783099
3.
Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani.
J Enzyme Inhib Med Chem
; 38(1): 2229071, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37381756
4.
Madurastatins with Imidazolidinone Rings: Natural Products or Side-Reaction Products from Extraction Solvents?
Int J Mol Sci
; 25(1)2023 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38203471
5.
Discovery of novel Leishmania major trypanothione synthetase inhibitors by high-throughput screening.
Biochem Biophys Res Commun
; 637: 308-313, 2022 12 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-36413853
6.
Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening.
J Enzyme Inhib Med Chem
; 37(1): 912-929, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35306933
7.
Discovery of Leishmania donovani topoisomerase IB selective inhibitors by targeting protein-protein interactions between the large and small subunits.
Biochem Biophys Res Commun
; 569: 193-198, 2021 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34256188
8.
Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani.
J Enzyme Inhib Med Chem
; 36(1): 1922-1930, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34425714
9.
Comparative study of different forms of Jellein antimicrobial peptide on Leishmania parasite.
Exp Parasitol
; 209: 107823, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31862270
10.
In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against Leishmania donovani and Trypanosoma brucei.
Molecules
; 25(8)2020 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32340370
11.
Spectroscopic and Computational Investigations of Ligand Binding to IspH: Discovery of Non-diphosphate Inhibitors.
Chembiochem
; 18(10): 914-920, 2017 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28253432
12.
Antileishmanial Mechanism of Diamidines Involves Targeting Kinetoplasts.
Antimicrob Agents Chemother
; 60(11): 6828-6836, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27600039
13.
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.
Antimicrob Agents Chemother
; 60(5): 2822-33, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26902771
14.
Phenolic Constituents of Medicinal Plants with Activity against Trypanosoma brucei.
Molecules
; 21(4): 480, 2016 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27077842
15.
In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates.
Antimicrob Agents Chemother
; 59(12): 7530-9, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26392508
16.
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.
Proc Natl Acad Sci U S A
; 109(11): 4058-63, 2012 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-22392982
17.
Secondary metabolites from Vietnamese marine invertebrates with activity against Trypanosoma brucei and T. cruzi.
Molecules
; 19(6): 7869-80, 2014 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24962391
18.
Identification of Novel Flavonoids and Ansa-Macrolides with Activities against Leishmania donovani through Natural Product Library Screening.
Pathogens
; 13(3)2024 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38535556
19.
Enhancing malaria detection in resource-limited areas: A high-performance colorimetric LAMP assay for Plasmodium falciparum screening.
PLoS One
; 19(2): e0298087, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38335219
20.
Bioorganometallic mechanism of action, and inhibition, of IspH.
Proc Natl Acad Sci U S A
; 107(10): 4522-7, 2010 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-20173096