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1.
Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans.
Drug Metab Dispos
; 50(5): 576-590, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35153195
2.
Effects of low temperature on blood-to-plasma ratio measurement.
Biopharm Drug Dispos
; 42(5): 234-241, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33625733
3.
6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1H-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to ß-Estradiol.
Drug Metab Dispos
; 46(12): 1836-1846, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30194276
4.
Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5'-Diphosphate-Glucuronosyltransferase Enzymes with Reference to Catalytic Activity.
Drug Metab Dispos
; 46(6): 805-812, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29581103
5.
The impact of low temperature on fraction unbound for plasma and tissue.
Biopharm Drug Dispos
; 39(9): 437-442, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30362129
6.
Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity.
Drug Metab Dispos
; 45(10): 1102-1112, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28768682
7.
Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis.
Chem Res Toxicol
; 29(10): 1778-1788, 2016 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27676153
8.
PF-07059013: A non-covalent hemoglobin modulator favorably impacts disease state in a mouse model of sickle cell disease.
Am J Hematol
; 96(8): E272-E275, 2021 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33891711
9.
Rural and Urban Home Modification Program Users: A Comparative Study.
HERD
; 16(2): 223-235, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36727246
10.
Evidence-based strategies for the characterisation of human drug and chemical glucuronidation in vitro and UDP-glucuronosyltransferase reaction phenotyping.
Pharmacol Ther
; 218: 107689, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32980440
11.
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease.
J Med Chem
; 64(1): 326-342, 2021 01 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33356244
12.
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Science
; 374(6575): 1586-1593, 2021 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34726479
13.
Estimation of the Effect of OAT2-Mediated Active Uptake on Meloxicam Exposure in the Human Liver.
AAPS J
; 22(2): 20, 2020 01 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31900711
14.
Evaluation of Fraction Unbound Across 7 Tissues of 5 Species.
J Pharm Sci
; 109(2): 1178-1190, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31704191
15.
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytes.
Eur J Pharm Sci
; 155: 105541, 2020 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32927071
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