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1.
Donor white blood cell differential is the single largest determinant of whole blood gene expression patterns.
Genomics
; 115(6): 110708, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37730167
2.
Large-scale informatic analysis to algorithmically identify blood biomarkers of neurological damage.
Proc Natl Acad Sci U S A
; 117(34): 20764-20775, 2020 08 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32764143
3.
Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts.
BMC Neurol
; 22(1): 206, 2022 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35659609
4.
Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkers.
Brain Inj
; 34(7): 965-974, 2020 06 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32497449
5.
High-throughput profiling of the circulating proteome suggests sexually dimorphic corticosteroid signaling following ischemic stroke.
Physiol Genomics
; 50(10): 876-883, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30029587
6.
Circulating leucocytes perpetuate stroke-induced aortic dysfunction.
Exp Physiol
; 102(10): 1321-1331, 2017 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28737253
7.
Circulating extracellular DNA levels are acutely elevated in ischaemic stroke and associated with innate immune system activation.
Brain Inj
; 31(10): 1369-1375, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28585898
8.
Interleukin-15 directly stimulates pro-oxidative gene expression in skeletal muscle in-vitro via a mechanism that requires interleukin-15 receptor alpha.
Biochem Biophys Res Commun
; 458(3): 614-619, 2015 Mar 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-25681766
9.
Dataset including whole blood gene expression profiles and matched leukocyte counts with utility for benchmarking cellular deconvolution pipelines.
BMC Genom Data
; 25(1): 45, 2024 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38714942
10.
Brain Expression Levels of Commonly Measured Blood Biomarkers of Neurological Damage Differ with Respect to Sex, Race, and Age.
Neuroscience
; 551: 79-93, 2024 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38762083
11.
Variability in donor leukocyte counts confound the use of common RNA sequencing data normalization strategies in transcriptomic biomarker studies performed with whole blood.
Sci Rep
; 13(1): 15514, 2023 09 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37726353
12.
Newly-identified blood biomarkers of neurological damage are correlated with infarct volume in patients with acute ischemic stroke.
J Clin Neurosci
; 94: 107-113, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34863423
13.
Optimized methodology for product recovery following emulsion PCR: applications for amplification of aptamer libraries and other complex templates.
J Biol Methods
; 7(1): e128, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32201710
14.
Diagnosis of ischemic stroke using circulating levels of brain-specific proteins measured via high-sensitivity digital ELISA.
Brain Res
; 1739: 146861, 2020 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32353434
15.
Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage.
Neurol Res
; 42(4): 346-353, 2020 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-32048573
16.
Neuro biomarker levels measured with high-sensitivity digital ELISA differ between serum and plasma.
Bioanalysis
; 11(22): 2087-2094, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31829739
17.
High-Throughput Profiling of Circulating Antibody Signatures for Stroke Diagnosis Using Small Volumes of Whole Blood.
Neurotherapeutics
; 16(3): 868-877, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30783962
18.
Shifts in Leukocyte Counts Drive the Differential Expression of Transcriptional Stroke Biomarkers in Whole Blood.
Transl Stroke Res
; 10(1): 26-35, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29550910
19.
Analysis of Early Stroke-induced Changes in Circulating Leukocyte Counts using Transcriptomic Deconvolution.
Transl Neurosci
; 9: 161-166, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30581599
20.
Stroke-associated pattern of gene expression previously identified by machine-learning is diagnostically robust in an independent patient population.
Genom Data
; 14: 47-52, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28932682