Detalles de la búsqueda
1.
Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor.
Circulation
; 148(2): 144-158, 2023 07 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37125593
2.
Efficacy and safety of ipragliflozin in Japanese patients with type 2 diabetes and inadequate glycaemic control on sitagliptin.
Diabetes Obes Metab
; 23(9): 2099-2108, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34033212
3.
A randomized, placebo-controlled trial to assess the efficacy and safety of sitagliptin in Japanese patients with type 2 diabetes and inadequate glycaemic control on ipragliflozin.
Diabetes Obes Metab
; 23(6): 1342-1350, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33565686
4.
A randomized, placebo-controlled study to evaluate the efficacy and safety of adding omarigliptin to insulin therapy in Japanese patients with type 2 diabetes and inadequate glycaemic control.
Diabetes Obes Metab
; 23(6): 1242-1251, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33512755
5.
Efficacy and safety of sitagliptin added to treatment of patients with type 2 diabetes inadequately controlled with premixed insulin.
Diabetes Obes Metab
; 21(2): 408-411, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30178570
6.
Double-blind, randomized clinical trial assessing the efficacy and safety of early initiation of sitagliptin during metformin uptitration in the treatment of patients with type 2 diabetes: The CompoSIT-M study.
Diabetes Obes Metab
; 21(5): 1128-1135, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30609212
7.
Double-blind, randomized clinical trial comparing the efficacy and safety of continuing or discontinuing the dipeptidyl peptidase-4 inhibitor sitagliptin when initiating insulin glargine therapy in patients with type 2 diabetes: The CompoSIT-I Study.
Diabetes Obes Metab
; 21(4): 781-790, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30393950
8.
A randomized clinical trial of the efficacy and safety of sitagliptin compared with dapagliflozin in patients with type 2 diabetes mellitus and mild renal insufficiency: The CompoSIT-R study.
Diabetes Obes Metab
; 20(12): 2876-2884, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30019498
9.
A randomized, placebo-controlled study of the cardiovascular safety of the once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus.
Cardiovasc Diabetol
; 16(1): 112, 2017 09 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28893244
10.
A randomized, placebo- and sitagliptin-controlled trial of the safety and efficacy of omarigliptin, a once-weekly dipeptidyl peptidase-4 inhibitor, in Japanese patients with type 2 diabetes.
Diabetes Obes Metab
; 19(11): 1602-1609, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28449368
11.
Randomized clinical trial comparing the efficacy and safety of treatment with the once-weekly dipeptidyl peptidase-4 (DPP-4) inhibitor omarigliptin or the once-daily DPP-4 inhibitor sitagliptin in patients with type 2 diabetes inadequately controlled on metformin monotherapy.
Diabetes Obes Metab
; 19(3): 394-400, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28093853
12.
A randomized, placebo-controlled clinical trial evaluating the safety and efficacy of the once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus inadequately controlled by glimepiride and metformin.
BMC Endocr Disord
; 17(1): 70, 2017 Nov 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29110647
13.
A randomised, double-blind, trial of the safety and efficacy of omarigliptin (a once-weekly DPP-4 inhibitor) in subjects with type 2 diabetes and renal impairment.
Int J Clin Pract
; 71(6)2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28449320
14.
Design, synthesis, and biological evaluation of aminopyrazine derivatives as inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
Bioorg Med Chem Lett
; 25(22): 5402-8, 2015 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26403928
15.
Single- and Multiple-Dose Pharmacokinetics of Gefapixant (MK-7264), a P2X3 Receptor Antagonist, in Healthy Adults.
J Clin Pharmacol
; 2024 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38651193
16.
Prevalence of low testosterone and its relationship to body mass index in older men with lower urinary tract symptoms associated with benign prostatic hyperplasia.
Aging Male
; 16(4): 169-72, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24134648
17.
Metabolic syndrome in mice induced by expressing a transcriptional activator in adipose tissue.
Transgenic Res
; 21(3): 633-44, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22038448
18.
Synthesis and biological activity of pyridopyridazin-6-one p38α MAP kinase inhibitors. Part 2.
Bioorg Med Chem Lett
; 22(18): 5979-83, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22901390
19.
A randomized clinical trial comparing point-of-care platelet function assays and bleeding time in healthy subjects treated with aspirin or clopidogrel.
Platelets
; 23(4): 249-58, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-21919555
20.
High-throughput simultaneous analysis of RNA, protein, and lipid biomarkers in heterogeneous tissue samples.
Clin Chem
; 57(11): 1545-55, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21914789