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1.
Tracking human neurologic disease status in mouse brain/plasma using reporter-tagged, EV-associated biomarkers.
Mol Ther
; 31(7): 2206-2219, 2023 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37198883
2.
Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver.
Drug Metab Dispos
; 51(1): 17-28, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36310032
3.
Estimation of fraction of drug metabolism by a single UDP-glucuronosyl transferase enzyme using relative expression factor.
Biopharm Drug Dispos
; 43(5): 213-217, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-36151066
4.
Large-scale multiplex absolute protein quantification of drug-metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH-MS: Comparison with MRM/SRM and HR-MRM/PRM.
Proteomics
; 16(15-16): 2106-17, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27197958
5.
Validation of uPA/SCID mouse with humanized liver as a human liver model: protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases by LC-MS/MS.
Drug Metab Dispos
; 42(6): 1039-43, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24711249
6.
Identification of transporters associated with Etoposide sensitivity of stomach cancer cell lines and methotrexate sensitivity of breast cancer cell lines by quantitative targeted absolute proteomics.
Mol Pharmacol
; 83(2): 490-500, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23197647
7.
Highly potent, orally active novel small-molecule HPK1 inhibitor DS21150768 induces anti-tumor responses in multiple syngeneic tumor mouse models.
Eur J Pharmacol
; 961: 176184, 2023 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37944847
8.
RNA interference activity of single-stranded oligonucleotides linked between the passenger strand and the guide strand with an aryl phosphate linker.
Nucleosides Nucleotides Nucleic Acids
; 40(6): 647-664, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34047248
9.
Design of 2'-O-methyl RNA and DNA double-stranded oligonucleotides: naturally-occurring nucleotide components with strong RNA interference gene expression inhibitory activity.
Nucleosides Nucleotides Nucleic Acids
; 39(1-3): 292-309, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-31509065
10.
Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics.
PLoS One
; 13(3): e0193799, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29513714
11.
A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood-brain barrier in ddY, FVB, and C57BL/6J mice.
Fluids Barriers CNS
; 10(1): 21, 2013 Jun 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-23758935
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