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1.
Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii.
Int J Clin Oncol
; 28(5): 613-624, 2023 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-36961615
2.
Activity of TAS4464, a novel NEDD8 activating enzyme E1 inhibitor, against multiple myeloma via inactivation of nuclear factor κB pathways.
Cancer Sci
; 110(12): 3802-3810, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31583781
3.
Fragment-Based Discovery of Allosteric Inhibitors of SH2 Domain-Containing Protein Tyrosine Phosphatase-2 (SHP2).
J Med Chem
; 67(6): 4655-4675, 2024 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38462716
4.
TAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia.
Oncogene
; 40(7): 1217-1230, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33420360
5.
Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors.
Cancer Res
; 80(22): 4986-4997, 2020 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32973082
6.
TAS4464, A Highly Potent and Selective Inhibitor of NEDD8-Activating Enzyme, Suppresses Neddylation and Shows Antitumor Activity in Diverse Cancer Models.
Mol Cancer Ther
; 18(7): 1205-1216, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31092565
7.
The novel VEGF receptor/MET-targeted kinase inhibitor TAS-115 has marked in vivo antitumor properties and a favorable tolerability profile.
Mol Cancer Ther
; 12(12): 2685-96, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24140932
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