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1.
Photoredox-based late-stage functionalization in SAR study for in vivo potent glucosylceramide synthase inhibitor.
Bioorg Med Chem Lett
; 77: 129039, 2022 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36341811
2.
Synthesis and evaluation of hedgehog signaling inhibitor with novel core system.
Bioorg Med Chem
; 23(15): 4777-4791, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26094943
3.
Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors.
Bioorg Med Chem
; 21(8): 2250-2261, 2013 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23490150
4.
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 2. Synthesis and characterization of a novel imide-type prodrug for improving oral absorption.
Bioorg Med Chem
; 20(15): 4680-92, 2012 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22763369
5.
Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: modification of the core skeleton for improved solubility.
Bioorg Med Chem
; 20(18): 5507-17, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22898254
6.
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.
Bioorg Med Chem
; 20(18): 5600-15, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22883026
7.
Discovery of pyrrolo[3,2-c]quinoline-4-one derivatives as novel hedgehog signaling inhibitors.
Bioorg Med Chem
; 20(18): 5496-506, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22910224
8.
Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.
J Med Chem
; 65(5): 4270-4290, 2022 03 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35188773
9.
Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain.
J Med Chem
; 64(16): 11990-12002, 2021 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34347478
10.
Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors.
PLoS One
; 15(10): e0240718, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33064779
11.
Neuromusculoskeletal model that walks and runs across a speed range with a few motor control parameter changes based on the muscle synergy hypothesis.
Sci Rep
; 9(1): 369, 2019 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-30674970
12.
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.
Nat Commun
; 8(1): 7, 2017 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28232751
13.
Perfect Composition Depth Profiling of Ionic Liquid Surfaces Using High-resolution RBS/ERDA.
Anal Sci
; 32(10): 1089-1094, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27725609
14.
Design and synthesis of pyrrolo[3,2-d]pyrimidine human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors: exploration of novel back-pocket binders.
J Med Chem
; 55(8): 3975-91, 2012 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22439974
15.
Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds.
J Med Chem
; 55(7): 3452-78, 2012 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22376051
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