Detalles de la búsqueda
1.
Pharmacological Profile of Difamilast, a Novel Selective Phosphodiesterase 4 Inhibitor, for Topical Treatment of Atopic Dermatitis.
J Pharmacol Exp Ther
; 386(1): 45-55, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37041087
2.
Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.
Nature
; 513(7519): 507-11, 2014 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-25231866
3.
Discovery of N-{2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-N'-[2-(propane-2-sulfonyl)phenyl]-1,3,5-triazine-2,4-diamine (ASP3026), a Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor.
Chem Pharm Bull (Tokyo)
; 66(3): 251-262, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29491259
4.
Modeling type II collagenopathy skeletal dysplasia by directed conversion and induced pluripotent stem cells.
Hum Mol Genet
; 24(2): 299-313, 2015 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25187577
5.
Characterization and Thermodynamic Stability of Polymorphs of Di(arylamino) Aryl Compound ASP3026.
Chem Pharm Bull (Tokyo)
; 63(6): 418-22, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26027465
6.
Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT2B and 5-HT7 receptor antagonists.
Bioorg Med Chem
; 22(21): 6026-38, 2014 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25281269
7.
Synthesis and structure-activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists. Part 2.
Bioorg Med Chem
; 22(15): 4323-37, 2014 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24916029
8.
Development of a novel marking system for laparoscopic gastrectomy using endoclips with radio frequency identification tags: feasibility study in a canine model.
Surg Endosc
; 28(9): 2752-9, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24651896
9.
Vaulted trans-bis(salicylaldiminato)platinum(II) crystals: heat-resistant, chromatically sensitive platforms for solid-state phosphorescence at ambient temperature.
Chemistry
; 19(15): 4798-811, 2013 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-23418050
10.
Synthesis and structure-activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists.
Bioorg Med Chem
; 21(24): 7841-52, 2013 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24189186
11.
Discovery of 2-methyl-1-{1-[(5-methyl-1H-indol-2-yl)carbonyl]piperidin-4-yl}propan-2-ol: a novel, potent and selective type 5 17ß-hydroxysteroid dehydrogenase inhibitor.
Bioorg Med Chem
; 21(17): 5261-70, 2013 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23845281
12.
The timing of retroviral silencing correlates with the quality of induced pluripotent stem cell lines.
Biochim Biophys Acta
; 1810(2): 226-35, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20965232
13.
Synthesis and pharmacological evaluation of 2-(1-alkylpiperidin-4-yl)-n-[(1r)-1-(4-fluorophenyl)-2-methylpropyl]acetamide Derivatives as Novel Antihypertensive Agents.
Chem Pharm Bull (Tokyo)
; 60(2): 223-34, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22293482
14.
Effective culture conditions for the induction of pluripotent stem cells.
Biochim Biophys Acta
; 1800(9): 956-63, 2010 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20417254
15.
Highly phosphorescent crystals of vaulted trans-bis(salicylaldiminato)platinum(II) complexes.
J Am Chem Soc
; 133(17): 6493-6, 2011 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21476542
16.
Induction of chondrogenic cells from dermal fibroblast culture by defined factors does not involve a pluripotent state.
Biochem Biophys Res Commun
; 411(3): 607-12, 2011 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-21763273
17.
Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.
Bioorg Med Chem
; 19(18): 5628-38, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21875808
18.
WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.
PLoS Genet
; 4(8): e1000171, 2008 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-18769712
19.
Synthesis and pharmacological evaluation of 1-isopropyl-1,2,3,4-tetrahydroisoquinoline derivatives as novel antihypertensive agents.
Chem Pharm Bull (Tokyo)
; 59(8): 1029-37, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21804249
20.
Synthesis and pharmacological evaluation of 1-alkyl-N-[(1R)-1-(4-fluorophenyl)-2-methylpropyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.
Chem Pharm Bull (Tokyo)
; 59(11): 1376-85, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22041074