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1.
Targeting of tumor growth and angiogenesis underlies the enhanced antitumor activity of lenvatinib in combination with everolimus.
Cancer Sci
; 108(4): 763-771, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28107584
2.
Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models.
Cancer Sci
; 105(10): 1334-42, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25060424
3.
Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.
Bioorg Med Chem
; 22(19): 5513-29, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25139751
4.
Expressions of cytochrome P450, UDP-glucuronosyltranferase, and transporter genes in monolayer carcinoma cells change in subcutaneous tumors grown as xenografts in immunodeficient nude mice.
Drug Metab Dispos
; 38(3): 526-33, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20007293
5.
Inoculation of human tumor cells alters the basal expression but not the inducibility of cytochrome P450 enzymes in tumor-bearing mouse liver.
Drug Metab Dispos
; 37(11): 2244-54, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19666990
6.
E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models.
Mol Cancer Ther
; 15(11): 2630-2639, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27535969
7.
Obesity and smoking: relationship with waist circumference and obesity-related disorders in men undergoing a health screening.
J Atheroscler Thromb
; 12(4): 199-204, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16141623
8.
Distinct binding mode of multikinase inhibitor lenvatinib revealed by biochemical characterization.
ACS Med Chem Lett
; 6(1): 89-94, 2015 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-25589937
9.
Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities.
J Antibiot (Tokyo)
; 57(3): 188-96, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-15152804
10.
[Treatment outcome of myelodysplastic syndrome patients younger than 60 years old].
Rinsho Ketsueki
; 44(10): 1004-9, 2003 Oct.
Artículo
en Japonés
| MEDLINE | ID: mdl-14639946
11.
Antitumor activity of lenvatinib (e7080): an angiogenesis inhibitor that targets multiple receptor tyrosine kinases in preclinical human thyroid cancer models.
J Thyroid Res
; 2014: 638747, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25295214
12.
Novel ATP-competitive MEK inhibitor E6201 is effective against vemurafenib-resistant melanoma harboring the MEK1-C121S mutation in a preclinical model.
Mol Cancer Ther
; 13(4): 823-32, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24448821
13.
Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models.
Cancer Lett
; 340(1): 97-103, 2013 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23856031
14.
Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor.
Int J Mol Med
; 29(4): 541-9, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22211243
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