Detalles de la búsqueda
1.
Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessus.
Antimicrob Agents Chemother
; 68(1): e0071723, 2024 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38018963
2.
Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing.
Proc Natl Acad Sci U S A
; 118(15)2021 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33766889
3.
SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development.
PLoS Pathog
; 17(2): e1009225, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33596266
4.
Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus.
Antimicrob Agents Chemother
; 66(9): e0066922, 2022 09 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-36005813
5.
Structure activity relationship of N-1 substituted 1,5-naphthyrid-2-one analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-9).
Bioorg Med Chem Lett
; 75: 128808, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35609741
6.
Gelatin expression from an engineered Saccharomyces cerevisiae CUP1 promoter in Pichia pastoris.
Yeast
; 38(6): 382-387, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33580598
7.
Intrathecal Morphine versus Intrathecal Hydromorphone for Analgesia after Cesarean Delivery: A Randomized Clinical Trial.
Anesthesiology
; 132(6): 1382-1391, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32251031
8.
Intensive versus conventional blood pressure monitoring in a general practice population. The Blood Pressure Reduction in Danish General Practice trial: a randomized controlled parallel group trial.
Fam Pract
; 35(4): 433-439, 2018 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-29351658
9.
Clinical implications of de Barsy syndrome.
Paediatr Anaesth
; 28(1): 59-62, 2018 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-29148179
10.
In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase.
Antimicrob Agents Chemother
; 60(8): 4830-9, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27246784
11.
FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition.
Pharm Res
; 33(8): 1833-49, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27059922
12.
Synthesis of amino heterocycle aspartyl protease inhibitors.
Org Biomol Chem
; 14(22): 4970-85, 2016 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27143279
13.
High-throughput enantiopurity analysis using enantiomeric DNA-based sensors.
J Am Chem Soc
; 137(12): 4198-206, 2015 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25747268
14.
Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5).
Bioorg Med Chem Lett
; 25(17): 3630-5, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26152426
15.
Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6).
Bioorg Med Chem Lett
; 25(17): 3636-43, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26141771
16.
Structure activity relationship of substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-4).
Bioorg Med Chem Lett
; 25(11): 2409-15, 2015 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25911300
17.
Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3).
Bioorg Med Chem Lett
; 25(12): 2473-8, 2015 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25978963
18.
Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2).
Bioorg Med Chem Lett
; 25(9): 1831-5, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25851938
19.
Kibdelomycin is a potent and selective agent against toxigenic Clostridium difficile.
Antimicrob Agents Chemother
; 58(4): 2387-92, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24514098
20.
Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.
PLoS Pathog
; 8(8): e1002895, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22952447