Detalles de la búsqueda
1.
Exploring the relationship between the conformation and pKa: can a pKa value be used to determine the conformational equilibrium?
Org Biomol Chem
; 13(10): 3116-21, 2015 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-25633433
2.
Design, synthesis and in vitro pharmacology of GluK1 and GluK3 antagonists. Studies towards the design of subtype-selective antagonists through 2-carboxyethyl-phenylalanines with substituents interacting with non-conserved residues in the GluK binding sites.
Bioorg Med Chem
; 22(19): 5368-77, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25172149
3.
Environmental and genetic variation in leaf anatomy among populations of Andropogon gerardii (Poaceae) along a precipitation gradient.
Am J Bot
; 100(10): 1957-68, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24061213
4.
Quantifying the electronic effects of carbohydrate hydroxy groups by using aminosugar models.
Chemistry
; 17(25): 7080-6, 2011 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21542038
5.
Eye movement suppression interferes with construction of object-centered spatial reference frames in working memory.
Brain Cogn
; 77(3): 432-7, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21907479
6.
Activation of Adenosine Monophosphate-Activated Protein Kinase Reduces the Onset of Diet-Induced Hepatocellular Carcinoma in Mice.
Hepatol Commun
; 4(7): 1056-1072, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32626837
7.
Synthesis of Shld Derivatives, Their Binding to the Destabilizing Domain, and Influence on Protein Accumulation in Transgenic Plants.
J Med Chem
; 62(10): 5191-5216, 2019 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31059249
8.
Determination of protonation states of iminosugar-enzyme complexes using photoinduced electron transfer.
Chem Sci
; 8(11): 7383-7393, 2017 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29163889
9.
Selenoureido-iminosugars: A new family of multitarget drugs.
Eur J Med Chem
; 123: 155-160, 2016 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27474931
10.
Intraspecific variation of a dominant grass and local adaptation in reciprocal garden communities along a US Great Plains' precipitation gradient: implications for grassland restoration with climate change.
Evol Appl
; 8(7): 705-23, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26240607
11.
A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions.
Angew Chem Int Ed Engl
; 42(22): 2507-11, 2003 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-12800172
12.
A fluorine scan at the catalytic center of thrombin: C--F, C--OH, and C--OMe bioisosterism and fluorine effects on pKa and log D values.
ChemMedChem
; 1(6): 611-21, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16892401
13.
Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors.
Org Biomol Chem
; 4(12): 2364-75, 2006 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-16763681
14.
Identification of potent and broad-spectrum antibiotics from SAR studies of a synthetic vancomycin analogue.
Bioorg Med Chem Lett
; 13(10): 1683-6, 2003 May 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-12729641
15.
Fluorine interactions at the thrombin active site: protein backbone fragments H-C(alpha)-C=O comprise a favorable C-F environment and interactions of C-F with electrophiles.
Chembiochem
; 5(5): 666-75, 2004 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-15122639
16.
A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C-F...CN interactions.
Org Biomol Chem
; 2(9): 1339-52, 2004 May 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-15105924
Resultados
1 -
16
de 16
1
Próxima >
>>