Detalles de la búsqueda
1.
Exploring the dual effect of novel 1,4-diarylpyranopyrazoles as antiviral and anti-inflammatory for the management of SARS-CoV-2 and associated inflammatory symptoms.
Bioorg Chem
; 130: 106255, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36403336
2.
Assessments of Alpha-Amylase Inhibitory Potential of Tagetes Flavonoids through In Vitro, Molecular Docking, and Molecular Dynamics Simulation Studies.
Int J Mol Sci
; 24(12)2023 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37373340
3.
Unveiling the Efficacy of Sesquiterpenes from Marine Sponge Dactylospongia elegans in Inhibiting Dihydrofolate Reductase Using Docking and Molecular Dynamic Studies.
Molecules
; 28(3)2023 Jan 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-36770958
4.
Structure-Based Virtual Screening and Molecular Dynamics Simulation Assessments of Depsidones as Possible Selective Cannabinoid Receptor Type 2 Agonists.
Molecules
; 28(4)2023 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36838749
5.
Fungal Bergamotane Sesquiterpenoids-Potential Metabolites: Sources, Bioactivities, and Biosynthesis.
Mar Drugs
; 20(12)2022 Dec 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36547918
6.
Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists.
Molecules
; 28(1)2022 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615238
7.
Advances in Fungal Phenaloenones-Natural Metabolites with Great Promise: Biosynthesis, Bioactivities, and an In Silico Evaluation of Their Potential as Human Glucose Transporter 1 Inhibitors.
Molecules
; 27(20)2022 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36296388
8.
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease.
Molecules
; 27(20)2022 Oct 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36296435
9.
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
J Enzyme Inhib Med Chem
; 36(1): 802-818, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33730937
10.
Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1,2,3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors: Synthesis, antitumor and mechanistic analyses.
Bioorg Chem
; 103: 104133, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32745759
11.
The rational design, synthesis, and antimicrobial investigation of 2-Amino-4-Methylthiazole analogues inhibitors of GlcN-6-P synthase.
Bioorg Chem
; 99: 103781, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32222620
12.
Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects.
Bioorg Chem
; 101: 103992, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32554279
13.
Introducing of potent cytotoxic novel 2-(aroylamino)cinnamamide derivatives against colon cancer mediated by dual apoptotic signal activation and oxidative stress.
Bioorg Chem
; 101: 103953, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32474179
14.
Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase.
Bioorg Chem
; 105: 104387, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33130344
15.
Antimicrobial screening and pharmacokinetic profiling of novel phenyl-[1,2,4]triazolo[4,3-a]quinoxaline analogues targeting DHFR and E. coli DNA gyrase B.
Bioorg Chem
; 96: 103656, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32062449
16.
Design, synthesis, molecular docking of new lipophilic acetamide derivatives affording potential anticancer and antimicrobial agents.
Bioorg Chem
; 76: 332-342, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29227917
17.
Design, Synthesis and Antiproliferative Activities of Oxidative Stress Inducers Based on 2-Styryl-3,5-dihydro-4H-imidazol-4-one Scaffold.
Chem Pharm Bull (Tokyo)
; 66(10): 967-975, 2018 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30047515
18.
Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor.
Molecules
; 22(2)2017 Jan 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-28125041
19.
Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin.
Molecules
; 21(8)2016 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-27529207
20.
Exploring antiproliferative activities and kinase profile of ortho-substituted N-(4-(2-(benzylamino)-2-oxoethyl)phenyl)benzamides.
Chem Biol Drug Des
; 103(1): e14379, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37873688