Detalles de la búsqueda
1.
Autophagy inhibition potentiates energy restriction-induced cell death in hepatocellular carcinoma cells.
IUBMB Life
; 2024 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38497226
2.
Phthalazone tethered 1,2,3-triazole conjugates: In silico molecular docking studies, synthesis, in vitro antiproliferative, and kinase inhibitory activities.
Bioorg Chem
; 133: 106404, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36812829
3.
New 1,2,3-triazole/1,2,4-triazole hybrids linked to oxime moiety as nitric oxide donor selective COX-2, aromatase, B-RAFV600E and EGFR inhibitors celecoxib analogs: design, synthesis, anti-inflammatory/anti-proliferative activities, apoptosis and molecular modeling study.
J Enzyme Inhib Med Chem
; 38(1): 2290461, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38061801
4.
Design, synthesis, and biological evaluation of a new series of pyrazole derivatives: Discovery of potent and selective JNK3 kinase inhibitors.
Bioorg Med Chem
; 69: 116894, 2022 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35764033
5.
Renoprotective effect of vinpocetine against ischemia/reperfusion injury: Modulation of NADPH oxidase/Nrf2, IKKß/NF-κB p65, and cleaved caspase-3 expressions.
J Biochem Mol Toxicol
; 36(7): e23046, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35315168
6.
Design, synthesis, and biological evaluation of novel pyrido-dipyrimidines as dual topoisomerase II/FLT3 inhibitors in leukemia cells.
Bioorg Chem
; 122: 105752, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35339926
7.
Multi-Omics Analysis Revealed a Significant Alteration of Critical Metabolic Pathways Due to Sorafenib-Resistance in Hep3B Cell Lines.
Int J Mol Sci
; 23(19)2022 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36233276
8.
Modulating NF-κB, MAPK, and PI3K/AKT signaling by ergothioneine attenuates iron overload-induced hepatocellular injury in rats.
J Biochem Mol Toxicol
; 35(5): e22729, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33580994
9.
Potential targeting of Hep3B liver cancer cells by lupeol isolated from Avicennia marina.
Arch Pharm (Weinheim)
; 354(9): e2100120, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-34085721
10.
PRMT5 Selective Inhibitor Enhances Therapeutic Efficacy of Cisplatin in Lung Cancer Cells.
Int J Mol Sci
; 22(11)2021 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34200178
11.
BACE1 inhibitors: Current status and future directions in treating Alzheimer's disease.
Med Res Rev
; 40(1): 339-384, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31347728
12.
Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways.
Toxicol Appl Pharmacol
; 391: 114919, 2020 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32045587
13.
Antiproliferative activity of cycloalkanecarboxamide derivatives possessing sulfonate or sulfamate moiety.
Bioorg Chem
; 97: 103677, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32120075
14.
Recent advances with alkaline phosphatase isoenzymes and their inhibitors.
Arch Pharm (Weinheim)
; 353(5): e2000011, 2020 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-32128876
15.
Sequencing [4 + 1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs.
J Org Chem
; 84(22): 14476-14486, 2019 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31633919
16.
Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities.
Bioorg Chem
; 91: 103132, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31374529
17.
Caffeic acid phenethyl ester guards against benign prostate hypertrophy in rats: Role of IGF-1R/protein kinase-B (Akt)/ß-catenin signaling.
IUBMB Life
; 70(6): 519-528, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29603556
18.
A neuroprotective role of kaempferol against chlorpyrifos-induced oxidative stress and memory deficits in rats via GSK3ß-Nrf2 signaling pathway.
Pestic Biochem Physiol
; 152: 29-37, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30497708
19.
Camel Milk Attenuates Rheumatoid Arthritis Via Inhibition of Mitogen Activated Protein Kinase Pathway.
Cell Physiol Biochem
; 43(2): 540-552, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28930753
20.
Caffeic acid phenethyl ester protects against glucocorticoid-induced osteoporosis in vivo: Impact on oxidative stress and RANKL/OPG signals.
Toxicol Appl Pharmacol
; 324: 26-35, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28363435