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1.
Loss of p53 drives neuron reprogramming in head and neck cancer.
Nature
; 578(7795): 449-454, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32051587
2.
Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.
Mol Cell
; 54(6): 960-974, 2014 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24857548
3.
FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner.
Clin Cancer Res
; 30(1): 187-197, 2024 01 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37819945
4.
TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV-associated oral squamous cell carcinoma.
J Immunother Cancer
; 11(8)2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37604640
5.
Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma.
Clin Cancer Res
; 29(7): 1344-1359, 2023 04 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36689560
6.
Mutant p53 drives an immune cold tumor immune microenvironment in oral squamous cell carcinoma.
Commun Biol
; 5(1): 757, 2022 07 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35902768
7.
Evolutionary Action Score of TP53 Analysis in Pathologically High-Risk Human Papillomavirus-Negative Head and Neck Cancer From a Phase 2 Clinical Trial: NRG Oncology Radiation Therapy Oncology Group 0234.
Adv Radiat Oncol
; 7(6): 100989, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36420184
8.
Biology of the Radio- and Chemo-Responsiveness in HPV Malignancies.
Semin Radiat Oncol
; 31(4): 274-285, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34455983
9.
Local Anti-PD-1 Delivery Prevents Progression of Premalignant Lesions in a 4NQO-Oral Carcinogenesis Mouse Model.
Cancer Prev Res (Phila)
; 14(8): 767-778, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34021022
10.
Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress.
Mol Cancer Ther
; 20(7): 1257-1269, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33947685
11.
Disruption of TP63-miR-27a* Feedback Loop by Mutant TP53 in Head and Neck Cancer.
J Natl Cancer Inst
; 112(3): 266-277, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31124563
12.
Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner ear.
Mol Cell Neurosci
; 38(2): 153-69, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18420419
13.
COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms.
Clin Cancer Res
; 25(18): 5650-5662, 2019 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31308060
14.
Head and neck cancer organoids established by modification of the CTOS method can be used to predict in vivo drug sensitivity.
Oral Oncol
; 87: 49-57, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30527243
15.
Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1.
Oncogene
; 37(10): 1279-1292, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29269868
16.
Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation.
Clin Cancer Res
; 23(21): 6541-6554, 2017 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28790110
17.
The final stage of cholinergic differentiation occurs below inner hair cells during development of the rodent cochlea.
J Assoc Res Otolaryngol
; 6(4): 401-15, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16228856
18.
Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins.
Clin Cancer Res
; 21(21): 4831-44, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26124202
19.
Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence.
Mol Cancer Ther
; 14(2): 608-19, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25504633
20.
Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer.
Cancer Res
; 75(7): 1527-36, 2015 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25634208