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1.
ABBV-0805, a novel antibody selective for soluble aggregated α-synuclein, prolongs lifespan and prevents buildup of α-synuclein pathology in mouse models of Parkinson's disease.
Neurobiol Dis
; 161: 105543, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34737044
2.
Amyloid-beta antibody binding to cerebral amyloid angiopathy fibrils and risk for amyloid-related imaging abnormalities.
Sci Rep
; 14(1): 10868, 2024 05 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38740836
3.
AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
J Neurochem
; 125(3): 446-56, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23410232
4.
Lecanemab, Aducanumab, and Gantenerumab - Binding Profiles to Different Forms of Amyloid-Beta Might Explain Efficacy and Side Effects in Clinical Trials for Alzheimer's Disease.
Neurotherapeutics
; 20(1): 195-206, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36253511
5.
Mechanism-based PK-PD model for the prolactin biological system response following an acute dopamine inhibition challenge: quantitative extrapolation to humans.
J Pharmacokinet Pharmacodyn
; 39(5): 463-77, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22791078
6.
Comparison of the agonist-antagonist interaction model and the pool model for the effect of remoxipride on prolactin.
Br J Clin Pharmacol
; 70(6): 815-24, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21175437
7.
How partnership should work to bring innovative medicines to patients.
Drug Discov Today
; 25(6): 965-968, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32173523
8.
Safety and tolerability of BAN2401--a clinical study in Alzheimer's disease with a protofibril selective Aß antibody.
Alzheimers Res Ther
; 8(1): 14, 2016 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27048170
9.
The murine version of BAN2401 (mAb158) selectively reduces amyloid-ß protofibrils in brain and cerebrospinal fluid of tg-ArcSwe mice.
J Alzheimers Dis
; 43(2): 575-88, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25096615
10.
Perspectives on future Alzheimer therapies: amyloid-ß protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer's disease.
Alzheimers Res Ther
; 6(2): 16, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25031633
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