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1.
Tumor eradication by triplet therapy with BRAF inhibitor, TLR 7 agonist, and PD-1 antibody for BRAF-mutated melanoma.
Cancer Sci
; 2024 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38894534
2.
Design, synthesis, and biological evaluation of phenylcyclopropylamine-entinostat conjugates that selectively target cancer cells.
Bioorg Med Chem
; 100: 117632, 2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38340642
3.
A Japanese multi-institutional phase II study of moderate hypofractionated intensity-modulated radiotherapy with image-guided technique for prostate cancer.
Int J Clin Oncol
; 29(6): 847-852, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38630382
4.
Real-world clinical outcomes in Japanese patients with locally advanced squamous cell carcinoma of the head and neck treated with radiotherapy plus cetuximab: a prospective observational study (JROSG12-2).
Int J Clin Oncol
; 27(11): 1675-1683, 2022 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-36001247
5.
Real-world clinical outcomes and prognostic factors in Japanese patients with recurrent or metastatic squamous cell carcinoma of head and neck treated with chemotherapy plus cetuximab: a prospective observation study (JROSG12-2).
Int J Clin Oncol
; 26(2): 316-325, 2021 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-33125596
6.
A phase II study of adaptive two-step intensity-modulated radiation therapy (IMRT) with chemotherapy for loco-regionally advanced nasopharyngeal cancer (JCOG1015).
Int J Clin Oncol
; 25(7): 1250-1259, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32221802
7.
HDAC8 inhibition ameliorates pulmonary fibrosis.
Am J Physiol Lung Cell Mol Physiol
; 316(1): L175-L186, 2019 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30358439
8.
Patient preference study comparing hypofractionated versus conventionally fractionated whole-breast irradiation after breast-conserving surgery.
Jpn J Clin Oncol
; 49(6): 545-553, 2019 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30796835
9.
Induction TPF chemotherapy followed by CRT with fractionated administration of cisplatin in patients with unresectable locally advanced head and neck cancer.
Int J Clin Oncol
; 24(7): 789-797, 2019 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-30796560
10.
Design, Synthesis, and Biological Evaluation of a Conjugate of 5-Fluorouracil and an LSD1 Inhibitor.
Chem Pharm Bull (Tokyo)
; 67(3): 192-195, 2019 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30369513
11.
Drug Design Concepts for LSD1-Selective Inhibitors.
Chem Rec
; 18(12): 1782-1791, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30277644
12.
Histone H3 peptides incorporating modified lysine residues as lysine-specific demethylase 1 inhibitors.
Bioorg Med Chem Lett
; 28(2): 167-169, 2018 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29198865
13.
Design, synthesis and evaluation of γ-turn mimetics as LSD1-selective inhibitors.
Bioorg Med Chem
; 26(3): 775-785, 2018 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29331452
14.
Design, Synthesis, and In Vitro Evaluation of Novel Histone H3 Peptide-Based LSD1 Inactivators Incorporating α,α-Disubstituted Amino Acids with γ-Turn-Inducing Structures.
Molecules
; 23(5)2018 05 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29734782
15.
Retrospective analysis of definitive radiotherapy for neck node metastasis from unknown primary tumor: Japanese Radiation Oncology Study Group study.
Jpn J Clin Oncol
; 47(9): 856-862, 2017 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28903529
16.
C-H activation enables a rapid structure-activity relationship study of arylcyclopropyl amines for potent and selective LSD1 inhibitors.
Org Biomol Chem
; 14(36): 8576-85, 2016 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-27548471
17.
False HDAC Inhibition by Aurone Compound.
Chem Pharm Bull (Tokyo)
; 64(8): 1124-8, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27477650
18.
Targeting Cancer with PCPA-Drug Conjugates: LSD1 Inhibition-Triggered Release of 4-Hydroxytamoxifen.
Angew Chem Int Ed Engl
; 55(52): 16115-16118, 2016 12 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-27882656
19.
TLR7 tolerance is independent of the type I IFN pathway and leads to loss of anti-tumor efficacy in mice.
Cancer Immunol Immunother
; 64(10): 1229-39, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26091797
20.
Histone H3 peptide based LSD1-selective inhibitors.
Bioorg Med Chem Lett
; 25(9): 1925-8, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25827526