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1.
In vitro antibacterial activity of AZD0914, a new spiropyrimidinetrione DNA gyrase/topoisomerase inhibitor with potent activity against Gram-positive, fastidious Gram-Negative, and atypical bacteria.
Antimicrob Agents Chemother
; 59(1): 467-74, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25385112
2.
Characterization of the novel DNA gyrase inhibitor AZD0914: low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae.
Antimicrob Agents Chemother
; 59(3): 1478-86, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25534723
3.
Microbiological interaction studies between ceftazidime-avibactam and pulmonary surfactant and between ceftazidime-avibactam and antibacterial agents of other classes.
Int J Antimicrob Agents
; 44(6): 552-6, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25293578
4.
Antibacterial inhibitors of Gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region.
J Med Chem
; 57(11): 4584-97, 2014 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24828090
5.
In vivo validation of thymidylate kinase (TMK) with a rationally designed, selective antibacterial compound.
ACS Chem Biol
; 7(11): 1866-72, 2012 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-22908966
6.
Discovery of selective and potent inhibitors of gram-positive bacterial thymidylate kinase (TMK).
J Med Chem
; 55(22): 10010-21, 2012 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23043329
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