Detalles de la búsqueda
1.
Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors.
Bioorg Med Chem
; 80: 117179, 2023 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36716583
2.
A New Drug Delivery System Based on Tauroursodeoxycholic Acid and PEDOT.
Chemistry
; 25(9): 2322-2329, 2019 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30537238
3.
Biochemically Controlled Release of Dexamethasone Covalently Bound to PEDOT.
Chemistry
; 24(41): 10300-10305, 2018 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29799647
4.
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification.
Anal Chem
; 88(19): 9510-9517, 2016 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27583774
5.
Fluorine nuclear magnetic resonance-based assay in living mammalian cells.
Anal Biochem
; 495: 52-9, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26686030
6.
Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis.
Angew Chem Int Ed Engl
; 55(37): 11193-11197, 2016 09 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27404798
7.
Fungal and bacterial species richness in biodeteriorated seventeenth century Venetian manuscripts.
Sci Rep
; 14(1): 7003, 2024 03 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38523163
8.
Computer-aided identification, synthesis, and biological evaluation of DNA polymerase η inhibitors for the treatment of cancer.
Eur J Med Chem
; 248: 115044, 2023 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36621139
9.
Quercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase.
Sci Rep
; 12(1): 10571, 2022 06 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35732785
10.
Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome.
J Med Chem
; 64(14): 10203-10229, 2021 07 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-34137257
11.
Design, Synthesis, Dynamic Docking, Biochemical Characterization, and in Vivo Pharmacokinetics Studies of Novel Topoisomerase II Poisons with Promising Antiproliferative Activity.
J Med Chem
; 63(7): 3508-3521, 2020 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32196342
12.
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation.
ChemMedChem
; 15(11): 949-954, 2020 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32267999
13.
Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors.
J Med Chem
; 63(24): 15821-15851, 2020 12 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-33290061
14.
Identification, Structure-Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators.
J Med Chem
; 63(19): 11169-11194, 2020 10 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32946228
15.
Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors.
J Med Chem
; 63(7): 3634-3664, 2020 04 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32176488
16.
Inhibition of Serine Palmitoyltransferase by a Small Organic Molecule Promotes Neuronal Survival after Astrocyte Amyloid Beta 1-42 Injury.
ACS Chem Neurosci
; 10(3): 1627-1635, 2019 03 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30481470
17.
Design, Synthesis, Structure-Activity Relationship Studies, and Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Modeling of a Series of O-Biphenyl Carbamates as Dual Modulators of Dopamine D3 Receptor and Fatty Acid Amide Hydrolase.
J Med Chem
; 60(6): 2287-2304, 2017 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28182408
18.
Potent α-amino-ß-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies.
Eur J Med Chem
; 111: 138-59, 2016 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-26866968
19.
O-(triazolyl)methyl carbamates as a novel and potent class of fatty acid amide hydrolase (FAAH) inhibitors.
ChemMedChem
; 10(2): 380-95, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25338703
20.
Hit Optimization of 5-Substituted-N-(piperidin-4-ylmethyl)-1H-indazole-3-carboxamides: Potent Glycogen Synthase Kinase-3 (GSK-3) Inhibitors with in Vivo Activity in Model of Mood Disorders.
J Med Chem
; 58(22): 8920-37, 2015 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26486317