Detalles de la búsqueda
1.
The fluorescence-based competitive counterflow assay developed for organic anion transporting polypeptides 1A2, 1B1, 1B3 and 2B1 identifies pentamidine as a selective OATP1A2 substrate.
FASEB J
; 37(11): e23223, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37781971
2.
Synthesis and in vitro photodynamic activity of aza-BODIPY-based photosensitizers.
Org Biomol Chem
; 21(29): 6018-6027, 2023 07 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37436113
3.
Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters.
Int J Mol Sci
; 24(14)2023 Jul 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37510996
4.
Organic Anion Transporting Polypeptide 3A1 (OATP3A1)-Gated Bio-Orthogonal Labeling of Intracellular Proteins.
Molecules
; 28(6)2023 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36985493
5.
8-acetoxy-trisulfopyrene as the first activatable fluorogenic probe for add-and-read assessment of Organic anion-transporting polypeptides, OATP1B1, OATP1B3, and OATP2B1.
FASEB J
; 35(9): e21863, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34411334
6.
Identifying Novel Inhibitors for Hepatic Organic Anion Transporting Polypeptides by Machine Learning-Based Virtual Screening.
J Chem Inf Model
; 62(24): 6323-6335, 2022 12 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35274943
7.
Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.
Int J Mol Sci
; 24(1)2022 Dec 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-36614037
8.
Selective antiproliferative effect of C-2 halogenated 13α-estrones on cells expressing Organic anion-transporting polypeptide 2B1 (OATP2B1).
Toxicol Appl Pharmacol
; 429: 115704, 2021 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34474082
9.
Data-Driven Ensemble Docking to Map Molecular Interactions of Steroid Analogs with Hepatic Organic Anion Transporting Polypeptides.
J Chem Inf Model
; 61(6): 3109-3127, 2021 06 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34105971
10.
Design, synthesis and biological evaluation of novel estrone phosphonates as high affinity organic anion-transporting polypeptide 2B1 (OATP2B1) inhibitors.
Bioorg Chem
; 112: 104914, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33932771
11.
Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters.
Drug Metab Dispos
; 48(10): 1064-1073, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32661014
12.
Identification of anticancer OATP2B1 substrates by an in vitro triple-fluorescence-based cytotoxicity screen.
Arch Toxicol
; 93(4): 953-964, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30863990
13.
Synthesis of Novel C-2- or C-15-Labeled BODIPY-Estrone Conjugates.
Molecules
; 23(4)2018 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29614041
14.
Pd-Catalyzed microwave-assisted synthesis of phosphonated 13α-estrones as potential OATP2B1, 17ß-HSD1 and/or STS inhibitors.
Beilstein J Org Chem
; 14: 2838-2845, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30498534
15.
Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter.
Biochim Biophys Acta
; 1848(2): 477-87, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25445676
16.
Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites.
Drug Metab Dispos
; 42(4): 575-85, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24384916
17.
Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein.
Biochem J
; 450(2): 387-95, 2013 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23205634
18.
The 2-aminoethyl diphenylborinate-based fluorescent method identifies quercetin and luteolin metabolites as substrates of Organic anion transporting polypeptides, OATP1B1 and OATP2B1.
Eur J Pharm Sci
; 196: 106740, 2024 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38437885
19.
Interaction of mycotoxins zearalenone, α-zearalenol, and ß-zearalenol with cytochrome P450 (CYP1A2, 2C9, 2C19, 2D6, and 3A4) enzymes and organic anion transporting polypeptides (OATP1A2, OATP1B1, OATP1B3, and OATP2B1).
Toxicol In Vitro
; 96: 105789, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38341109
20.
Synthesis and estrogenic activity of BODIPY-labeled estradiol conjugates.
Eur J Pharm Sci
; 199: 106813, 2024 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38797442