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1.
Knock-in mice expressing a humanized arachidonic acid 15-lipoxygenase (Alox15) carry a partly dysfunctional erythropoietic system.
Cell Mol Biol Lett
; 28(1): 97, 2023 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38030974
2.
Humanization of the Reaction Specificity of Mouse Alox15b Inversely Modified the Susceptibility of Corresponding Knock-In Mice in Two Different Animal Inflammation Models.
Int J Mol Sci
; 24(13)2023 Jul 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37446212
3.
Direct and indirect modulation of LPS-induced cytokine production by insulin in human macrophages.
Cytokine
; 136: 155241, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32799102
4.
The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism.
Hepatology
; 66(2): 616-630, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28133767
5.
Induction of steatohepatitis (NASH) with insulin resistance in wildtype B6 mice by a western-type diet containing soybean oil and cholesterol.
Mol Med
; 23: 70-82, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28332698
6.
Insulin-induced cytokine production in macrophages causes insulin resistance in hepatocytes.
Am J Physiol Endocrinol Metab
; 310(11): E938-46, 2016 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27094035
7.
Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype.
Diabetologia
; 57(2): 373-82, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24292566
8.
Determining On-Target, Off-Target, and Copy Number Status of Transgenic Events After CRISPR/Cas9 Targeted AAVS1 Safe-Harbor Modification of iPSCs Using Double-Control Quantitative Copy Number PCR.
Curr Protoc
; 3(1): e635, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36598341
9.
LDL-Dependent Regulation of TNFα/PGE2 Induced COX-2/mPGES-1 Expression in Human Macrophage Cell Lines.
Inflammation
; 46(3): 893-911, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36598592
10.
Stimulation of fat accumulation in hepatocytes by PGE2-dependent repression of hepatic lipolysis, ß-oxidation and VLDL-synthesis.
Lab Invest
; 92(11): 1597-606, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22964849
11.
Female mice are more susceptible to nonalcoholic fatty liver disease: sex-specific regulation of the hepatic AMP-activated protein kinase-plasminogen activator inhibitor 1 cascade, but not the hepatic endotoxin response.
Mol Med
; 18: 1346-55, 2012 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-22952059
12.
Macrophages, Low-Grade Inflammation, Insulin Resistance and Hyperinsulinemia: A Mutual Ambiguous Relationship in the Development of Metabolic Diseases.
J Clin Med
; 11(15)2022 Jul 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35955975
13.
Validation of a Novel Double Control Quantitative Copy Number PCR Method to Quantify Off-Target Transgene Integration after CRISPR-Induced DNA Modification.
Methods Protoc
; 5(3)2022 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35736544
14.
Discrimination of the Activity of Low-Affinity Wild-Type and High-Affinity Mutant Recombinant BoNT/B by a SIMA Cell-Based Reporter Release Assay.
Toxins (Basel)
; 14(1)2022 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35051041
15.
The Reaction Specificity of Mammalian ALOX15 Orthologs is Changed During Late Primate Evolution and These Alterations Might Offer Evolutionary Advantages for Hominidae.
Front Cell Dev Biol
; 10: 871585, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35531094
16.
Male Knock-in Mice Expressing an Arachidonic Acid Lipoxygenase 15B (Alox15B) with Humanized Reaction Specificity Are Prematurely Growth Arrested When Aging.
Biomedicines
; 10(6)2022 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35740398
17.
Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle.
Nutr Diabetes
; 12(1): 20, 2022 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35418570
18.
Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis.
Lab Invest
; 91(7): 1107-17, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21519329
19.
Cell-Based Reporter Release Assay to Determine the Activity of Calcium-Dependent Neurotoxins and Neuroactive Pharmaceuticals.
Toxins (Basel)
; 13(4)2021 03 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33808507
20.
Enhanced Palmitate-Induced Interleukin-8 Formation in Human Macrophages by Insulin or Prostaglandin E2.
Biomedicines
; 9(5)2021 Apr 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33919366