Detalles de la búsqueda
1.
Population pharmacokinetic characteristics of cemiplimab in patients with advanced malignancies.
J Pharmacokinet Pharmacodyn
; 48(4): 479-494, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33728546
2.
Safety and tolerability of subcutaneous sarilumab and intravenous tocilizumab in patients with rheumatoid arthritis.
Rheumatology (Oxford)
; 58(5): 849-858, 2019 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30590833
3.
Delamanid Coadministered with Antiretroviral Drugs or Antituberculosis Drugs Shows No Clinically Relevant Drug-Drug Interactions in Healthy Subjects.
Antimicrob Agents Chemother
; 60(10): 5976-85, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27458223
4.
Immunogenicity of Cemiplimab: Low Incidence of Antidrug Antibodies and Cut-Point Suitability Across Tumor Types.
J Clin Pharmacol
; 64(1): 125-136, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37656820
5.
Subcutaneous Administration of Monoclonal Antibodies: Pharmacology, Delivery, Immunogenicity, and Learnings From Applications to Clinical Development.
Clin Pharmacol Ther
; 115(3): 422-439, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38093583
6.
Safety and Immune Responses Following Anti-PD-1 Monoclonal Antibody Infusions in Healthy Persons With Human Immunodeficiency Virus on Antiretroviral Therapy.
Open Forum Infect Dis
; 11(3): ofad694, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38449916
7.
High response rate with extended dosing of cemiplimab in advanced cutaneous squamous cell carcinoma.
J Immunother Cancer
; 12(3)2024 03 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38471711
8.
Population pharmacokinetics modeling and exposure-response analyses of cemiplimab in patients with recurrent or metastatic cervical cancer.
CPT Pharmacometrics Syst Pharmacol
; 11(11): 1458-1471, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36251220
9.
Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial.
Nat Med
; 28(11): 2374-2380, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36008722
10.
Pharmacokinetics and Pharmacodynamics of Subcutaneous Sarilumab and Intravenous Tocilizumab Following Single-Dose Administration in Patients With Active Rheumatoid Arthritis on Stable Methotrexate.
J Clin Pharmacol
; 61(1): 90-104, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32726514
11.
Differential Binding of Sarilumab and Tocilizumab to IL-6Rα and Effects of Receptor Occupancy on Clinical Parameters.
J Clin Pharmacol
; 61(5): 714-724, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33314148
12.
Fixed Dose of Cemiplimab in Patients with Advanced Malignancies Based on Population Pharmacokinetic Analysis.
Adv Ther
; 38(5): 2365-2378, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33768419
13.
Bioanalytical Challenges due to Prior Checkpoint Inhibitor Exposure: Interference and Mitigation in Drug Concentration and Immunogenicity Assays.
AAPS J
; 23(6): 109, 2021 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34608545
14.
Dose exploration results from Phase 1 study of cemiplimab, a human monoclonal programmed death (PD)-1 antibody, in Japanese patients with advanced malignancies.
Cancer Chemother Pharmacol
; 87(1): 53-64, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33146741
15.
Population Pharmacokinetic-Pharmacodynamic Relationships of Sarilumab Using Disease Activity Score 28-Joint C-Reactive Protein and Absolute Neutrophil Counts in Patients with Rheumatoid Arthritis.
Clin Pharmacokinet
; 59(11): 1451-1466, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32451909
16.
Population Pharmacodynamic Model of Neutrophil Margination and Tolerance to Describe Effect of Sarilumab on Absolute Neutrophil Count in Patients with Rheumatoid Arthritis.
CPT Pharmacometrics Syst Pharmacol
; 9(7): 405-416, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32453485
17.
First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low-dose Cyclophosphamide in Patients with Advanced Malignancies.
Clin Cancer Res
; 26(5): 1025-1033, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31796520
18.
Population Pharmacokinetics of Sarilumab in Patients with Rheumatoid Arthritis.
Clin Pharmacokinet
; 58(11): 1455-1467, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31055792
19.
Immunogenicity of Sarilumab Monotherapy in Patients with Rheumatoid Arthritis Who Were Inadequate Responders or Intolerant to Disease-Modifying Antirheumatic Drugs.
Rheumatol Ther
; 6(3): 339-352, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31090044
20.
Disease-Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis.
Clin Pharmacokinet
; 56(6): 607-615, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27722854