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1.
Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations.
Arch Biochem Biophys
; 729: 109392, 2022 10 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36096178
2.
Insights into the pathogenesis of primary hyperoxaluria type I from the structural dynamics of alanine:glyoxylate aminotransferase variants.
FEBS Lett
; 598(4): 485-499, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38243391
3.
Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme.
FEBS J
; 290(7): 1855-1873, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36378023
4.
Structural dynamics at the active site of the cancer-associated flavoenzyme NQO1 probed by chemical modification with PMSF.
FEBS Lett
; 597(21): 2687-2698, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37726177
5.
Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme.
Lab Chip
; 23(13): 3016-3033, 2023 06 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37294576
6.
Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1.
J Pers Med
; 12(5)2022 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35629169
7.
Loss of stability and unfolding cooperativity in hPGK1 upon gradual structural perturbation of its N-terminal domain hydrophobic core.
Sci Rep
; 12(1): 17200, 2022 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36229482
8.
Effect of naturally-occurring mutations on the stability and function of cancer-associated NQO1: Comparison of experiments and computation.
Front Mol Biosci
; 9: 1063620, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36504709
9.
Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations.
Antioxidants (Basel)
; 11(6)2022 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35740007
10.
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation.
FEBS Lett
; 596(1): 29-41, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34817874
11.
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue.
Redox Biol
; 46: 102112, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34537677
12.
Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein.
J Pers Med
; 10(4)2020 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33153185
13.
Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability.
Int J Biol Macromol
; 125: 1275-1288, 2019 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30243998
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