Detalles de la búsqueda
1.
A phase 3b study of venetoclax and azacitidine or decitabine in an outpatient setting in patients with acute myeloid leukemia.
Hematol Oncol
; 42(3): e3274, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38711253
2.
A Phase 3b Study for Management of Ocular Side Effects in Patients with Epidermal Growth Factor Receptor-Amplified Glioblastoma Receiving Depatuxizumab Mafodotin.
Ophthalmic Res
; 66(1): 1030-1043, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37257422
3.
Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of pain.
Bioorg Med Chem
; 63: 116743, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35436748
4.
Pharmacology of modality-specific transient receptor potential vanilloid-1 antagonists that do not alter body temperature.
J Pharmacol Exp Ther
; 342(2): 416-28, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22570364
5.
Synthesis and evaluation of 2-amido-3-carboxamide thiophene CB2 receptor agonists for pain management.
Bioorg Med Chem Lett
; 22(7): 2604-8, 2012 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22370265
6.
Impact of venetoclax monotherapy on the quality of life of patients with relapsed or refractory chronic lymphocytic leukemia: results from the phase 3b VENICE II trial.
Leuk Lymphoma
; 63(2): 304-314, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34632935
7.
Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord.
Mol Pain
; 7: 39, 2011 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-21599960
8.
Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2,2,3,3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], using in vitro pharmacological assays, in vivo pain models, and pharmacological magnetic resonance imaging.
J Pharmacol Exp Ther
; 328(1): 141-51, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18931146
9.
Indol-3-yl-tetramethylcyclopropyl ketones: effects of indole ring substitution on CB2 cannabinoid receptor activity.
J Med Chem
; 51(6): 1904-12, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18311894
10.
Updated quality of life data from the phase 3b VENICE II trial: patients with relapsed or refractory chronic lymphocytic leukemia receiving venetoclax monotherapy.
Leuk Lymphoma
; : 1-4, 2023 Aug 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37626019
11.
Substituted Indazoles as Nav1.7 Blockers for the Treatment of Pain.
J Med Chem
; 59(7): 3373-91, 2016 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27015369
12.
Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models.
J Pain
; 15(4): 387.e1-14, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24374196
13.
Disturbances in slow-wave sleep are induced by models of bilateral inflammation, neuropathic, and postoperative pain, but not osteoarthritic pain in rats.
Pain
; 154(7): 1092-102, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23664655
14.
Pharmacological characterization of A-960656, a histamine H3 receptor antagonist with efficacy in animal models of osteoarthritis and neuropathic pain.
Eur J Pharmacol
; 684(1-3): 87-94, 2012 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-22504024
15.
Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats.
Br J Pharmacol
; 162(2): 428-40, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20880025
16.
Potentiation of analgesic efficacy but not side effects: co-administration of an α4ß2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in experimental models of pain in rats.
Biochem Pharmacol
; 82(8): 967-76, 2011 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21620806
17.
Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems.
Brain Res
; 1354: 74-84, 2010 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20682302
18.
H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats.
Pharmacol Biochem Behav
; 95(1): 41-50, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20004681
19.
Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity.
J Med Chem
; 53(1): 295-315, 2010 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19921781
20.
Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis.
Eur J Pharmacol
; 613(1-3): 39-45, 2009 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-19376109