Detalles de la búsqueda
1.
pH-Responsive Trihydroxylated Piperidines Rescue The Glucocerebrosidase Activity in Human Fibroblasts Bearing The Neuronopathic Gaucher-Related L444P/L444P Mutations in GBA1 Gene.
Chembiochem
; 25(1): e202300730, 2024 01 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37877519
2.
Iminosugar-dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers.
Chem Biodivers
; : e202401104, 2024 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38847390
3.
Light-Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones.
Chemistry
; 29(19): e202203841, 2023 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36598148
4.
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy.
FASEB J
; 36(12): e22655, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36421008
5.
Gold nanoparticles decorated with monosaccharides and sulfated ligands as potential modulators of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS).
Org Biomol Chem
; 21(47): 9362-9371, 2023 12 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37975191
6.
Evaluating comprehensive cancer networks; a review of standards and evaluation methods for care networks to inform a comparison with the OECI comprehensive cancer network standards.
Acta Oncol
; 62(1): 15-24, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36786345
7.
3,4,5-Trihydroxypiperidine Based Multivalent Glucocerebrosidase (GCase) Enhancers.
Chembiochem
; 23(11): e202200077, 2022 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35322924
8.
Photoswitchable inhibitors of human ß-glucocerebrosidase.
Org Biomol Chem
; 20(8): 1637-1641, 2022 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-35107482
9.
Differential impact of cold and hot tea extracts on tyrosine phosphatases regulating insulin receptor activity: a focus on PTP1B and LMW-PTP.
Eur J Nutr
; 61(4): 1905-1918, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35066640
10.
uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells.
Cell Mol Life Sci
; 78(6): 3057-3072, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33237352
11.
Insights into Cytotoxic Behavior of Lepadins and Structure Elucidation of the New Alkaloid Lepadin L from the Mediterranean Ascidian Clavelina lepadiformis.
Mar Drugs
; 20(1)2022 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35049920
12.
Synthesis of a New ß-Galactosidase Inhibitor Displaying Pharmacological Chaperone Properties for GM1 Gangliosidosis.
Molecules
; 27(13)2022 Jun 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35807262
13.
Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction.
Circ Res
; 124(8): e44-e54, 2019 04 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30732554
14.
Dual Targeting of PTP1B and Aldose Reductase with Marine Drug Phosphoeleganin: A Promising Strategy for Treatment of Type 2 Diabetes.
Mar Drugs
; 19(10)2021 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34677434
15.
Natural α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitors: A Source of Scaffold Molecules for Synthesis of New Multitarget Antidiabetic Drugs.
Molecules
; 26(16)2021 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34443409
16.
In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications-A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B.
Molecules
; 26(2)2021 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33435264
17.
miR-210-3p mediates metabolic adaptation and sustains DNA damage repair of resistant colon cancer cells to treatment with 5-fluorouracil.
Mol Carcinog
; 58(12): 2181-2192, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31468617
18.
Morin-dependent inhibition of low molecular weight protein tyrosine phosphatase (LMW-PTP) restores sensitivity to apoptosis during colon carcinogenesis: Studies in vitro and in vivo, in an Apc-driven model of colon cancer.
Mol Carcinog
; 58(5): 686-698, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30582224
19.
LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy.
Cancer Cell Int
; 19: 67, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30948927
20.
Highly Charged Ruthenium(II) Polypyridyl Complexes as Effective Photosensitizer in Photodynamic Therapy.
Chemistry
; 25(45): 10606-10615, 2019 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31107567