Detalles de la búsqueda
1.
Design, Synthesis, Biological Evaluation and In Silico Study of Benzyloxybenzaldehyde Derivatives as Selective ALDH1A3 Inhibitors.
Molecules
; 26(19)2021 Sep 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-34641313
2.
Structural and kinetic features of aldehyde dehydrogenase 1A (ALDH1A) subfamily members, cancer stem cell markers active in retinoic acid biosynthesis.
Arch Biochem Biophys
; 681: 108256, 2020 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31923393
3.
Synthesis of C11-to-C14 methyl-shifted all-trans-retinal analogues and their activities on human aldo-keto reductases.
Org Biomol Chem
; 18(25): 4788-4801, 2020 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32530010
4.
Enantioselective Synthesis of Vicinal (R,R)-Diols by Saccharomyces cerevisiae Butanediol Dehydrogenase.
Appl Environ Microbiol
; 82(6): 1706-1721, 2016 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26729717
5.
The Xenopus alcohol dehydrogenase gene family: characterization and comparative analysis incorporating amphibian and reptilian genomes.
BMC Genomics
; 15: 216, 2014 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-24649825
6.
Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 3): 889-903, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24598757
7.
Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin.
Cell Mol Life Sci
; 68(6): 1065-77, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20835842
8.
Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.
Biochem J
; 440(3): 335-44, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21851338
9.
Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3.
Commun Biol
; 5(1): 354, 2022 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35418200
10.
Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer.
J Med Chem
; 65(5): 3833-3848, 2022 03 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35212533
11.
Perspective on the Structural Basis for Human Aldo-Keto Reductase 1B10 Inhibition.
Metabolites
; 11(12)2021 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34940623
12.
Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3.
J Biol Chem
; 284(25): 17194-17205, 2009 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-19349281
13.
Role of Saccharomyces cerevisiae oxidoreductases Bdh1p and Ara1p in the metabolism of acetoin and 2,3-butanediol.
Appl Environ Microbiol
; 76(3): 670-9, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19966022
14.
Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10.
Proc Natl Acad Sci U S A
; 104(52): 20764-9, 2007 Dec 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-18087047
15.
Engineering aldo-keto reductase 1B10 to mimic the distinct 1B15 topology and specificity towards inhibitors and substrates, including retinoids and steroids.
Chem Biol Interact
; 307: 186-194, 2019 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31028727
16.
Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
Chem Biol Interact
; 306: 123-130, 2019 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30958995
17.
Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiation.
Sci Rep
; 9(1): 3177, 2019 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30816220
18.
Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase.
Eur J Med Chem
; 152: 160-174, 2018 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29705708
19.
Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.
Biochem J
; 399(1): 101-9, 2006 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16787387
20.
Characterization of AKR1B16, a novel mouse aldo-keto reductase.
Chem Biol Interact
; 276: 182-193, 2017 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28322781