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1.
Systemic bacterial infections affect dendritic cell development and function.
Int J Med Microbiol
; 311(6): 151517, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34233227
2.
RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella.
J Infect Dis
; 217(8): 1257-1266, 2018 03 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29325043
3.
A Brucella spp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+ T Cell Responses.
J Immunol
; 196(10): 4014-29, 2016 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27084100
4.
Innate immune system favors emergency monopoiesis at the expense of DC-differentiation to control systemic bacterial infection in mice.
Eur J Immunol
; 45(10): 2821-33, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26138432
5.
Depletion of dendritic cells enhances innate anti-bacterial host defense through modulation of phagocyte homeostasis.
PLoS Pathog
; 8(2): e1002552, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22383883
6.
A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection.
Nat Commun
; 15(1): 997, 2024 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38307851
7.
Safety and immunogenicity of a SARS-CoV-2 Gamma variant RBD-based protein adjuvanted vaccine used as booster in healthy adults.
Nat Commun
; 14(1): 4551, 2023 07 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37507392
8.
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
J Immunol
; 184(9): 5200-12, 2010 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20351187
9.
A disordered region retains the full protease inhibitor activity and the capacity to induce CD8+ T cells in vivo of the oral vaccine adjuvant U-Omp19.
Comput Struct Biotechnol J
; 20: 5098-5114, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36187929
10.
A Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice.
Front Immunol
; 13: 844837, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35296091
11.
Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosis.
Am J Pathol
; 176(3): 1323-38, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20093491
12.
Stability Studies of the Vaccine Adjuvant U-Omp19.
J Pharm Sci
; 110(2): 707-718, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33058898
13.
U-Omp19 from Brucella abortus increases dmLT immunogenicity and improves protection against Escherichia coli heat-labile toxin (LT) oral challenge.
Vaccine
; 38(32): 5027-5035, 2020 07 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32536545
14.
Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+ and CD8+ T cells as well as systemic and oral protection against Brucella abortus infection.
Infect Immun
; 77(1): 436-45, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18981242
15.
Oral co-administration of a bacterial protease inhibitor in the vaccine formulation increases antigen delivery at the intestinal epithelial barrier.
J Control Release
; 293: 158-171, 2019 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30496771
16.
Omp19 Enables Brucella abortus to Evade the Antimicrobial Activity From Host's Proteolytic Defense System.
Front Immunol
; 10: 1436, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31297115
17.
Brucella abortus inhibits major histocompatibility complex class II expression and antigen processing through interleukin-6 secretion via Toll-like receptor 2.
Infect Immun
; 76(1): 250-62, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17984211
18.
Brucella lipoproteins mimic dendritic cell maturation induced by Brucella abortus.
Microbes Infect
; 10(12-13): 1346-54, 2008 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-18761420
19.
U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice.
Front Immunol
; 8: 171, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28261222
20.
Brucella abortus Omp19 recombinant protein subcutaneously co-delivered with an antigen enhances antigen-specific T helper 1 memory responses and induces protection against parasite challenge.
Vaccine
; 34(4): 430-437, 2016 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26707377