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1.
Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.
Mol Cell
; 54(6): 960-974, 2014 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-24857548
2.
Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress.
Mol Cancer Ther
; 20(7): 1257-1269, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33947685
3.
Disruption of TP63-miR-27a* Feedback Loop by Mutant TP53 in Head and Neck Cancer.
J Natl Cancer Inst
; 112(3): 266-277, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31124563
4.
COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms.
Clin Cancer Res
; 25(18): 5650-5662, 2019 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31308060
5.
Head and neck cancer organoids established by modification of the CTOS method can be used to predict in vivo drug sensitivity.
Oral Oncol
; 87: 49-57, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30527243
6.
Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1.
Oncogene
; 37(10): 1279-1292, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29269868
7.
Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation.
Clin Cancer Res
; 23(21): 6541-6554, 2017 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28790110
8.
Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins.
Clin Cancer Res
; 21(21): 4831-44, 2015 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26124202
9.
Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence.
Mol Cancer Ther
; 14(2): 608-19, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25504633
10.
Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients.
Cancer Res
; 75(7): 1205-15, 2015 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25691460
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