Detalles de la búsqueda
1.
Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.
N Engl J Med
; 382(20): 1883-1893, 2020 05 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32222134
2.
Classification of Heart Failure Events by Severity: Insights From the VICTORIA Trial.
J Card Fail
; 29(8): 1113-1120, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37331690
3.
WCK 1152, WCK 1153: Discovery and structure activity relationship for the treatment of resistant pneumococcal and staphylococcal respiratory infections.
Bioorg Med Chem Lett
; 63: 128665, 2022 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35276361
4.
WCK 4034: A promising oxazolidinone for treating gram positive infections.
Bioorg Med Chem Lett
; 71: 128842, 2022 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35680102
5.
Medication use by US patients with pulmonary hypertension associated with chronic obstructive pulmonary disease: a retrospective study of administrative data.
BMC Pulm Med
; 22(1): 383, 2022 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36258171
6.
Preclinical safety evaluation of levonadifloxacin, a novel anti-methicillin-resistant Staphyloccocus aureus benzoquinolizine fluoroquinolone by intravenous and oral administration.
J Appl Toxicol
; 42(8): 1354-1370, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35146781
7.
Ensuring robustness in the quality of antibiotic susceptibility test discs for four novel antibiotics.
Biomed Chromatogr
; 36(6): e5354, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35141944
8.
In vitro evolution of cefepime/zidebactam (WCK 5222) resistance in Pseudomonas aeruginosa: dynamics, mechanisms, fitness trade-off and impact on in vivo efficacy.
J Antimicrob Chemother
; 76(10): 2546-2557, 2021 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34219168
9.
Representativeness of the VICTORIA Trial Population in Clinical Practice: Analysis of the PINNACLE Registry.
J Card Fail
; 27(12): 1374-1381, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34271161
10.
Design and synthesis of an oral prodrug alalevonadifloxacin for the treatment of MRSA infection.
Bioorg Med Chem Lett
; 54: 128432, 2021 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34757217
11.
Assessment of the in vitro cytochrome P450 (CYP) inhibition potential of nafithromycin, a next generation lactone ketolide antibiotic.
Xenobiotica
; 51(3): 251-261, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33078993
12.
Preclinical safety evaluation of nafithromycin (WCK 4873) with emphasis on liver safety in rat and dog.
Regul Toxicol Pharmacol
; 122: 104889, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33587936
13.
Asymptomatic SARS-CoV-2 Infection and COVID-19 Mortality During an Outbreak Investigation in a Skilled Nursing Facility.
Clin Infect Dis
; 71(11): 2920-2926, 2020 12 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-32548628
14.
Levonadifloxacin, a Novel Benzoquinolizine Fluoroquinolone, Modulates Lipopolysaccharide-Induced Inflammatory Responses in Human Whole-Blood Assay and Murine Acute Lung Injury Model.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32152077
15.
Effective inhibition of PBPs by cefepime and zidebactam in the presence of VIM-1 drives potent bactericidal activity against MBL-expressing Pseudomonas aeruginosa.
J Antimicrob Chemother
; 75(6): 1474-1478, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32083659
16.
Activity of cefepime/zidebactam against MDR Escherichia coli isolates harbouring a novel mechanism of resistance based on four-amino-acid inserts in PBP3.
J Antimicrob Chemother
; 75(12): 3563-3567, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32772098
17.
The Pathologic Peritoneal Cancer Index (PCI) Strongly Differs From the Surgical PCI in Peritoneal Metastases Arising From Various Primary Tumors.
Ann Surg Oncol
; 27(8): 2985-2996, 2020 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-32040698
18.
Assessment of in vitro inhibitory effects of novel anti MRSA benzoquinolizine fluoroquinolone WCK 771 (levonadifloxacin) and its metabolite on human liver cytochrome P450 enzymes.
Xenobiotica
; 50(10): 1149-1157, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32283993
19.
Clinical Implications of Negatively Adjudicated Heart Failure Events: Data From the VICTORIA Study.
Circulation
; 147(8): 694-696, 2023 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36802884
20.
In Vivo Pharmacokinetic/Pharmacodynamic Targets of Levonadifloxacin against Staphylococcus aureus in a Neutropenic Murine Lung Infection Model.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31208999