Detalles de la búsqueda
1.
Assessment of the in vitro cytochrome P450 (CYP) inhibition potential of ZYTP1, a novel poly (ADP-ribose) polymerase inhibitor.
Xenobiotica
; 49(10): 1164-1172, 2019 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30488748
2.
Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models.
Liver Int
; 38(6): 1084-1094, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29164820
3.
Sensitive and specific LC-ESI-MS/MS method for determination of ZYDPLA1, a novel long-acting dipeptidyl peptidase 4 inhibitor in rat plasma: An application for toxicokinetic study in rats.
Biomed Chromatogr
; 31(11)2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28370279
4.
ZYBT1, a potent, irreversible Bruton's Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer.
Pharmacol Res Perspect
; 8(4): e00565, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32790160
5.
Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a CB1 receptor antagonist with in vivo antiobesity effect.
Bioorg Med Chem Lett
; 19(9): 2546-50, 2009 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19328683
6.
Subtherapeutic dose of pioglitazone reduces expression of inflammatory adipokines in db/db mice.
Pharmacology
; 84(4): 203-10, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19738399
7.
Biological approach to treatment of intra-articular proximal tibial fractures with double osteosynthesis.
Int Orthop
; 33(1): 271-4, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18038135
8.
Pharmacological inhibition of prolyl hydroxylase protects against inflammation-induced anemia via efficient erythropoiesis and hepcidin downregulation.
Eur J Pharmacol
; 843: 113-120, 2019 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30458168
9.
Lack of inhibition of CYP2C8 by saroglitazar magnesium: In vivo assessment using montelukast, rosiglitazone, pioglitazone, repaglinide and paclitaxel as victim drugs in Wistar rats.
Eur J Pharm Sci
; 130: 107-113, 2019 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30633968
10.
Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor beta (TR-beta) selective ligands.
Bioorg Med Chem Lett
; 18(14): 3919-24, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18585912
11.
Facile synthesis, ex-vivo and in vitro screening of 3-sulfonamide derivative of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide (SR141716) a potent CB1 receptor antagonist.
Bioorg Med Chem Lett
; 18(14): 3882-6, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18585913
12.
Bioisosteric replacement of dihydropyrazole of 4S-(-)-3-(4-chlorophenyl)-N-methyl-N'-[(4-chlorophenyl)-sulfonyl]-4-phenyl-4,5-dihydro-1H-pyrazole-1-caboxamidine (SLV-319) a potent CB1 receptor antagonist by imidazole and oxazole.
Bioorg Med Chem Lett
; 18(3): 963-8, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18207393
13.
In vitro PAI-1 inhibitory activity of oxalamide derivatives.
Eur J Med Chem
; 43(4): 880-4, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17664030
14.
Synthesis and in vitro antibacterial activities of novel oxazolidinones.
Eur J Med Chem
; 43(4): 683-93, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17611001
15.
Antithrombotic effects due to pharmacological modulation of thrombin-activatable fibrinolysis inhibitor in rats.
Pharmacology
; 82(4): 304-9, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18936552
16.
An approach to floating knee injury in Indian Population: An analysis of 52 patients.
Indian J Orthop
; 52(6): 631-637, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30532304
17.
Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1.
Cancer Chemother Pharmacol
; 82(4): 635-647, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30046848
18.
Diaryl dihydropyrazole-3-carboxamides with significant in vivo antiobesity activity related to CB1 receptor antagonism: synthesis, biological evaluation, and molecular modeling in the homology model.
J Med Chem
; 50(24): 5951-66, 2007 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-17979261
19.
HPV vaccines: Global perspectives.
Hum Vaccin Immunother
; 13(6): 1-4, 2017 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28362244
20.
ZY15557, a novel, long acting inhibitor of dipeptidyl peptidase-4, for the treatment of Type 2 diabetes mellitus.
Br J Pharmacol
; 174(14): 2346-2357, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-28452143