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1.
Assessment of metabolic stability and pharmacokinetics by LC-MS/MS and establishment of the safe dose of IMID-2, a novel anticancer molecule under drug discovery.
Biomed Chromatogr
; 37(6): e5618, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36882885
2.
Boronic acid derivative activates pyruvate kinase M2 indispensable for redox metabolism in oral cancer cells.
Bioorg Med Chem Lett
; 59: 128539, 2022 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35007726
3.
Discovery of boronic acid-based potent activators of tumor pyruvate kinase M2 and development of gastroretentive nanoformulation for oral dosing.
Bioorg Med Chem Lett
; 42: 128062, 2021 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33901643
4.
Pyruvate kinase M2 in chronic inflammations: a potpourri of crucial protein-protein interactions.
Cell Biol Toxicol
; 37(5): 653-678, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33864549
5.
Metabolite profiling of IMID-2, a novel anticancer molecule of piperazine derivative: In silico prediction, in vitro and in vivo metabolite characterization using UPLC-QTOF-MS/MS.
Biomed Chromatogr
; 35(6): e5082, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33570183
6.
Potassium tert-butoxide mediated C-C, C-N, C-O and C-S bond forming reactions.
Org Biomol Chem
; 18(41): 8346-8365, 2020 11 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33020791
7.
Drug development and bioanalytical method validation for a novel anticancer molecule, 4-(dimethylamino)-2-(p-tolylamino) thiazole-5-carbonitrile.
Drug Dev Res
; 79(8): 391-399, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30329161
8.
Intramolecular Acylation of Unactivated Pyridines or Arenes via Multiple C-H Functionalizations: Synthesis of All Four Azafluorenones and Fluorenones.
J Org Chem
; 82(1): 76-85, 2017 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27966934
9.
Stability-Indicating TLC-Densitometric and HPLC Methods for Simultaneous Determination of Teneligliptin and Pioglitazone in Pharmaceutical Dosage Forms with Eco-Friendly Assessment.
J Chromatogr Sci
; 2024 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38836346
10.
Attack detection and mitigation scheme through novel authentication model enabled optimized neural network in smart healthcare.
Comput Methods Biomech Biomed Engin
; 26(1): 38-64, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-35243937
11.
Objective assessment of adrenocortical carcinoma driver genes and their correlation with tumor pyruvate kinase M2.
Gene
; 822: 146354, 2022 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35189247
12.
Novel imidazopyrimidines-based molecules induce tetramerization of tumor pyruvate kinase M2 and exhibit potent antiproliferative profile.
Eur J Pharm Sci
; 170: 106112, 2022 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34971746
13.
Tumor pyruvate kinase M2 modulators: a comprehensive account of activators and inhibitors as anticancer agents.
RSC Med Chem
; 12(7): 1121-1141, 2021 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34355179
14.
Design, computational studies, synthesis and biological evaluation of thiazole-based molecules as anticancer agents.
Eur J Pharm Sci
; 134: 20-30, 2019 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30965082
15.
Scope of Successive C-H Functionalizations of the Methyl Group in 3-Picolines: Intramolecular Carbonylation of Arenes to the Metal-Free Synthesis of 4-Azafluorenones.
Org Lett
; 17(23): 5890-3, 2015 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26587583
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