Detalles de la búsqueda
1.
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features.
Biol Chem
; 2024 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38373142
2.
Multifunctional NK Cell-Engaging Antibodies Targeting EGFR and NKp30 Elicit Efficient Tumor Cell Killing and Proinflammatory Cytokine Release.
J Immunol
; 209(9): 1724-1735, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36104113
3.
Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement.
J Immunol
; 206(1): 225-236, 2021 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33268483
4.
Antibody display technologies: selecting the cream of the crop.
Biol Chem
; 403(5-6): 455-477, 2022 04 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-33759431
5.
Development of a c-MET x CD137 bispecific antibody for targeted immune agonism in cancer immunotherapy.
Cancer Treat Res Commun
; 39: 100805, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38492435
6.
Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers.
MAbs
; 16(1): 2315640, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38372053
7.
Facile One-Step Generation of Camelid VHH and Avian scFv Libraries for Phage Display by Golden Gate Cloning.
Methods Mol Biol
; 2681: 47-60, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37405642
8.
Isolation of Antigen-Specific Unconventional Bovine Ultra-Long CDR3H Antibodies Using Cattle Immunization in Combination with Yeast Surface Display.
Methods Mol Biol
; 2681: 113-129, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37405646
9.
One-Pot Droplet RT-OE-PCR for the Generation of Natively Paired Antibody Immune Libraries.
Methods Mol Biol
; 2681: 213-229, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37405650
10.
Affinity Maturation of the Natural Ligand (B7-H6) for Natural Cytotoxicity Receptor NKp30 by Yeast Surface Display.
Methods Mol Biol
; 2681: 231-248, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37405651
11.
Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format.
Front Immunol
; 14: 1238313, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37942319
12.
A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization.
MAbs
; 15(1): 2261149, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37766540
13.
NKp46-specific single domain antibodies enable facile engineering of various potent NK cell engager formats.
Protein Sci
; 32(3): e4593, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36775946
14.
Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition.
MAbs
; 15(1): 2236265, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37469014
15.
AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study.
Front Mol Biosci
; 10: 1249247, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37842638
16.
Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities.
MAbs
; 14(1): 2018960, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35014603
17.
Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of 'Almost Natural' Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection.
Front Immunol
; 12: 801368, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-35087526
18.
Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity.
Front Immunol
; 12: 742418, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34759924
19.
Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform.
MAbs
; 12(1): 1812210, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32887531
20.
A One-Step Process for the Construction of Phage Display scFv and VHH Libraries.
Mol Biotechnol
; 62(4): 228-239, 2020 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-31981039