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1.
Phosphorylation of enteroviral 2Apro at Ser/Thr125 benefits its proteolytic activity and viral pathogenesis.
J Med Virol
; 95(1): e28400, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36511115
2.
USP39 Serves as a Deubiquitinase to Stabilize STAT1 and Sustains Type I IFN-Induced Antiviral Immunity.
J Immunol
; 205(11): 3167-3178, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33127822
3.
Discovery of 3-benzyl-1,3-benzoxazine-2,4-dione analogues as allosteric mitogen-activated kinase kinase (MEK) inhibitors and anti-enterovirus 71 (EV71) agents.
Bioorg Med Chem
; 24(16): 3472-82, 2016 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27288186
4.
D-Isonucleotide (isoNA) incorporation around cleavage site of passenger strand promotes the vibration of Ago2-PAZ domain and enhances in vitro potency of siRNA.
Org Biomol Chem
; 13(44): 10825-33, 2015 Nov 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26313718
5.
[Distribution in different Salmonella serovars and integration sites of Salmonella paratyphi C phage SPC-P1].
Beijing Da Xue Xue Bao Yi Xue Ban
; 47(6): 914-9, 2015 Dec 18.
Artículo
en Zh
| MEDLINE | ID: mdl-26679650
6.
Substituted 3-benzylcoumarins as allosteric MEK1 inhibitors: design, synthesis and biological evaluation as antiviral agents.
Molecules
; 18(5): 6057-91, 2013 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23698055
7.
Discovery of HPG1860, a Structurally Novel Nonbile Acid FXR Agonist Currently in Clinical Development for the Treatment of Nonalcoholic Steatohepatitis.
J Med Chem
; 66(14): 9363-9375, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37424079
8.
A lysosomes and mitochondria dual-targeting AIE-active NIR photosensitizer: Constructing amphiphilic structure for enhanced antitumor activity and two-photon imaging.
Mater Today Bio
; 21: 100721, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37502829
9.
Long-Term Infection and Pathogenesis in a Novel Mouse Model of Human Respiratory Syncytial Virus.
Viruses
; 14(8)2022 08 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36016362
10.
Cellular Caspase-3 Contributes to EV-A71 2Apro-Mediated Down-Regulation of IFNAR1 at the Translation Level.
Virol Sin
; 35(1): 64-72, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31512106
11.
Hybrids of MEK inhibitor and NO donor as multitarget antitumor drugs.
Eur J Med Chem
; 196: 112271, 2020 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32305784
12.
Effects of combined exposure to perfluoroalkyl acids and heavy metals on bioaccumulation and subcellular distribution in earthworms (Eisenia fetida) from co-contaminated soil.
Environ Sci Pollut Res Int
; 25(29): 29335-29344, 2018 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-30121767
13.
Substituted 3-benzylcoumarins 13 and 14 suppress enterovirus A71 replication by impairing viral 2Apro dependent IRES-driven translation.
Antiviral Res
; 160: 10-16, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30315876
14.
Single-step construction of a picornavirus replicon RNA with precise ends.
J Virol Methods
; 248: 87-91, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28629711
15.
Regulation of enterovirus 2A protease-associated viral IRES activities by the cell's ERK signaling cascade: Implicating ERK as an efficiently antiviral target.
Antiviral Res
; 143: 13-21, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28351508
16.
Gene sequencing and variable site analyzing of coding region of two enterovirus A71 isolates with different clinical phenotypes.
Infect Genet Evol
; 45: 83-89, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27566335
17.
Both ERK1 and ERK2 are required for enterovirus 71 (EV71) efficient replication.
Viruses
; 7(3): 1344-56, 2015 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25803100
18.
The multi-targeted kinase inhibitor sorafenib inhibits enterovirus 71 replication by regulating IRES-dependent translation of viral proteins.
Antiviral Res
; 106: 80-5, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24680956
19.
A 3C(pro)-dependent bioluminescence imaging assay for in vivo evaluation of anti-enterovirus 71 agents.
Antiviral Res
; 101: 82-92, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24263113
20.
MEK1-ERKs signal cascade is required for the replication of Enterovirus 71 (EV71).
Antiviral Res
; 93(1): 110-7, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22101247