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1.
Improved Controlled Release and Brain Penetration of the Small Molecule S14 Using PLGA Nanoparticles.
Int J Mol Sci
; 22(6)2021 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-33809846
2.
Isoquinoline Alkaloids from Berberis vulgaris as Potential Lead Compounds for the Treatment of Alzheimer's Disease.
J Nat Prod
; 82(2): 239-248, 2019 02 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-30701972
3.
Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3.
J Enzyme Inhib Med Chem
; 34(1): 87-96, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30362380
4.
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier.
Molecules
; 24(7)2019 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30959739
5.
1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders.
J Enzyme Inhib Med Chem
; 33(1): 665-670, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29536773
6.
In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier.
J Nat Prod
; 78(6): 1189-92, 2015 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-26030662
7.
Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3ß inhibitors.
Angew Chem Int Ed Engl
; 54(5): 1578-82, 2015 Jan 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-25504761
8.
Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models.
Eur J Med Chem
; 245(Pt 1): 114923, 2023 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36423450
9.
Protein kinases CK1 and CK2 as new targets for neurodegenerative diseases.
Med Res Rev
; 31(6): 924-54, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20577972
10.
Increasing Brain Permeability of PHA-767491, a Cell Division Cycle 7 Kinase Inhibitor, with Biodegradable Polymeric Nanoparticles.
Pharmaceutics
; 13(2)2021 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33525757
11.
Developing novel classes of protein kinase CK1δ inhibitors by fusing [1,2,4]triazole with different bicyclic heteroaromatic systems.
Eur J Med Chem
; 216: 113331, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33721670
12.
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis.
Eur J Med Chem
; 210: 112968, 2021 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33139113
13.
The first enantioselective synthesis of palinurin.
Chem Commun (Camb)
; (22): 3252-4, 2009 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19587930
14.
Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools.
Bioorg Med Chem
; 17(19): 6914-25, 2009 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19747834
15.
A Triazolotriazine-Based Dual GSK-3ß/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition.
ChemMedChem
; 14(3): 310-314, 2019 02 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30548443
16.
GSK-3 inhibitors: a ray of hope for the treatment of Alzheimer's disease?
J Alzheimers Dis
; 15(2): 181-91, 2008 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-18953107
17.
Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors.
Eur J Med Chem
; 145: 431-444, 2018 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29335209
18.
Drugs in clinical development for the treatment of amyotrophic lateral sclerosis.
Expert Opin Investig Drugs
; 26(4): 403-414, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28277881
19.
Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease.
ACS Omega
; 2(8): 5215-5220, 2017 Aug 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-30023743
20.
Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agents.
Eur J Med Chem
; 138: 328-342, 2017 Sep 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-28688273