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1.
cGAS-STING signalling regulates microglial chemotaxis in genome instability.
Nucleic Acids Res
; 52(3): 1188-1206, 2024 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38084916
2.
Tau and Amyloid ß Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiation in Vivo.
J Neurosci
; 43(32): 5870-5879, 2023 08 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37491315
3.
Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes.
Gene Ther
; 30(1-2): 132-141, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35637286
4.
P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
Brain Behav Immun
; 114: 414-429, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37716378
5.
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins.
Acta Neuropathol
; 139(3): 503-526, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31853635
6.
Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau In Vivo.
J Neurosci
; 38(50): 10595-10606, 2018 12 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30355631
7.
Soluble tau aggregates inhibit synaptic long-term depression and amyloid ß-facilitated LTD in vivo.
Neurobiol Dis
; 127: 582-590, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30910746
8.
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.
Neurobiol Dis
; 132: 104582, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31445162
9.
Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease.
Alzheimers Dement
; 15(3): 487-496, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30419228
10.
Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aß production.
Hum Mol Genet
; 22(22): 4646-52, 2013 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23825109
11.
Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aß production.
Hum Mol Genet
; 21(13): 2845-54, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22434822
12.
Pharmacokinetics of AAV9 Mediated Trastuzumab Expression in Rat Brain Following Systemic and Local Administration.
J Pharm Sci
; 113(1): 131-140, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37659717
13.
GULP1 is a novel APP-interacting protein that alters APP processing.
Biochem J
; 436(3): 631-9, 2011 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21486224
14.
New Therapeutics in Alzheimer's Disease Longitudinal Cohort study (NTAD): study protocol.
BMJ Open
; 12(12): e055135, 2022 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36521898
15.
X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice.
Hum Mol Genet
; 18(23): 4492-500, 2009 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19744962
16.
Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production.
J Neurosci
; 29(14): 4442-60, 2009 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-19357271
17.
Amyloid precursor protein 695 associates with assembled NR2A- and NR2B-containing NMDA receptors to result in the enhancement of their cell surface delivery.
J Neurochem
; 111(6): 1501-13, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19811606
18.
Increased Foxo3a Nuclear Translocation and Activity is an Early Neuronal Response to ßγ-Secretase-Mediated Processing of the Amyloid-ß Protein Precursor: Utility of an AßPP-GAL4 Reporter Assay.
J Alzheimers Dis
; 61(2): 673-688, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29254083
19.
Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways.
Cell Rep
; 22(13): 3612-3624, 2018 03 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29590627
20.
Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy.
Acta Neuropathol Commun
; 6(1): 65, 2018 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-30037345