Detalles de la búsqueda
1.
Inhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma.
Eur Respir J
; 61(3)2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36822634
2.
Safety, Pharmacokinetics, and Causal Prophylactic Efficacy of KAF156 in a Plasmodium falciparum Human Infection Study.
Clin Infect Dis
; 73(7): e2407-e2414, 2021 10 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32644127
3.
Phase 2 Study of Anti-Human Cytomegalovirus Monoclonal Antibodies for Prophylaxis in Hematopoietic Cell Transplantation.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32015031
4.
Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria.
N Engl J Med
; 375(12): 1152-60, 2016 09 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27653565
5.
A First-in-Human Study To Assess the Safety and Pharmacokinetics of Monoclonal Antibodies against Human Cytomegalovirus in Healthy Volunteers.
Antimicrob Agents Chemother
; 60(5): 2881-7, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26926639
6.
Pharmacokinetics of LFF571 and vancomycin in patients with moderate Clostridium difficile infections.
Antimicrob Agents Chemother
; 59(3): 1441-5, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25534724
7.
Multicenter, randomized clinical trial to compare the safety and efficacy of LFF571 and vancomycin for Clostridium difficile infections.
Antimicrob Agents Chemother
; 59(3): 1435-40, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25534727
8.
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel antimalarial Spiroindolone KAE609 (Cipargamin) to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers.
Antimicrob Agents Chemother
; 58(10): 6209-14, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25114127
9.
A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel Imidazolopiperazine KAF156 to assess its safety, tolerability, and pharmacokinetics in healthy adult volunteers.
Antimicrob Agents Chemother
; 58(11): 6437-43, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25136017
10.
A first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study to assess the safety and tolerability of LFF571 in healthy volunteers.
Antimicrob Agents Chemother
; 56(11): 5946-51, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22964250
11.
Shared Learnings on the New EMA First-in-Human and Early Clinical Trial Guideline: Proceedings From a DIAlogue Session at DIA Europe 2018.
Ther Innov Regul Sci
; 54(2): 462-467, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32072587
12.
Effects of prior effective therapy on the efficacy of daptomycin and ceftriaxone for the treatment of community-acquired pneumonia.
Clin Infect Dis
; 46(8): 1142-51, 2008 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18444848
13.
Safety, tolerability, pharmacokinetics, and efficacy of an interleukin-2 agonist among HIV-infected patients receiving highly active antiretroviral therapy.
J Interferon Cytokine Res
; 28(2): 89-100, 2008 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18279104
14.
Eradication of common pathogens at days 2, 3 and 4 of moxifloxacin therapy in patients with acute bacterial sinusitis.
BMC Ear Nose Throat Disord
; 6: 8, 2006 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-16646958
15.
Sequential intravenous/oral moxifloxacin versus intravenous piperacillin-tazobactam followed by oral amoxicillin-clavulanate for the treatment of complicated skin and skin structure infection.
Int J Antimicrob Agents
; 26(5): 357-65, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16229991
16.
Clinical characteristics and functional outcomes of West Nile Fever.
Ann Intern Med
; 141(5): 360-5, 2004 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-15353427
17.
Linezolid treatment for osteomyelitis due to vancomycin-resistant Enterococcus faecium.
Clin Infect Dis
; 34(10): 1412-4, 2002 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-11981739
18.
Comparison of a 3-day with a 1-day regimen of an extended-release formulation of ciprofloxacin as antimicrobial prophylaxis for patients undergoing transrectal needle biopsy of the prostate.
BJU Int
; 100(1): 51-7, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17552953
19.
Risk factors for a poor outcome after therapy for acute pyelonephritis.
BJU Int
; 98(1): 141-7, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16831159
20.
Randomized controlled trial of moxifloxacin compared with piperacillin-tazobactam and amoxicillin-clavulanate for the treatment of complicated intra-abdominal infections.
Ann Surg
; 244(2): 204-11, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16858182