Detalles de la búsqueda
1.
Fast deep learning reconstruction techniques for preclinical magnetic resonance fingerprinting.
NMR Biomed
; 37(1): e5028, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37669779
2.
Heterogeneity of Neuroinflammatory Responses in Amyotrophic Lateral Sclerosis: A Challenge or an Opportunity?
Int J Mol Sci
; 21(21)2020 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33113845
3.
Metallothioneins are neuroprotective agents in lysosomal storage disorders.
Ann Neurol
; 83(2): 418-432, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29369397
4.
Hydrazone linked doxorubicin-PLA prodrug nanoparticles with high drug loading.
Nanotechnology
; 29(30): 305602, 2018 Jul 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-29701613
5.
Development of easy-to-use reverse-phase liquid chromatographic methods for determining PRE-084, RC-33 and RC-34 in biological matrices. The first step for in vivo analysis of sigma1 receptor agonists.
Biomed Chromatogr
; 30(4): 645-51, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26447185
6.
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.
Neurobiol Dis
; 62: 218-32, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24141020
7.
Identification of RC-33 as a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability.
Bioorg Med Chem
; 21(9): 2577-86, 2013 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23498917
8.
Studies on the enantiomers of RC-33 as neuroprotective agents: isolation, configurational assignment, and preliminary biological profile.
Chirality
; 25(11): 814-22, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24038285
9.
An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model.
EMBO Mol Med
; 15(4): e15968, 2023 04 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36876653
10.
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.
Eur J Med Chem
; 249: 115163, 2023 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36716640
11.
Discovery of RC-752, a Novel Sigma-1 Receptor Antagonist with Antinociceptive Activity: A Promising Tool for Fighting Neuropathic Pain.
Pharmaceuticals (Basel)
; 16(7)2023 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37513874
12.
Neuroprotective effects of toll-like receptor 4 antagonism in spinal cord cultures and in a mouse model of motor neuron degeneration.
Mol Med
; 18: 971-81, 2012 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22562723
13.
Identification of a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells.
Bioorg Med Chem
; 19(21): 6210-24, 2011 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21967807
14.
Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System.
Front Genome Ed
; 3: 644319, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34713256
15.
Synthesis and Characterization of a "Clickable" PBR28 TSPO-Selective Ligand Derivative Suitable for the Functionalization of Biodegradable Polymer Nanoparticles.
Nanomaterials (Basel)
; 11(7)2021 Jun 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34203263
16.
Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization.
J Med Chem
; 64(20): 14997-15016, 2021 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34624193
17.
Lipophilic dye-compatible brain clearing technique allowing correlative magnetic resonance/high-resolution fluorescence imaging in rat models of glioblastoma.
Sci Rep
; 10(1): 17974, 2020 10 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33087842
18.
Biodegradable polymeric nanoparticles administered in the cerebrospinal fluid: Brain biodistribution, preferential internalization in microglia and implications for cell-selective drug release.
Biomaterials
; 209: 25-40, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31026609
19.
Simultaneous Flow Cytometric Characterization of Multiple Cell Types Retrieved from Mouse Brain/Spinal Cord Through Different Homogenization Methods.
J Vis Exp
; (153)2019 11 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31814622
20.
Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells.
Sci Adv
; 3(12): e1701211, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29226242