Detalles de la búsqueda
1.
Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance.
Diabetologia
; 58(4): 799-808, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25596852
2.
Benzimidazole-carboxamides as potent and bioavailable stearoyl-CoA desaturase (SCD1) inhibitors from ligand-based virtual screening and chemical optimization.
Bioorg Med Chem Lett
; 23(6): 1817-22, 2013 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23395660
3.
Multi attribute method implementation using a High Resolution Mass Spectrometry platform: From sample preparation to batch analysis.
PLoS One
; 17(1): e0262711, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35085302
4.
Automated mass spectrometry multi-attribute method analyses for process development and characterization of mAbs.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1166: 122540, 2021 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33545564
5.
Management of nicotinamide N-methyltransferase overexpression: inhibit the enzyme or reduce nicotinamide intake? Reply to Zhou S, Li D, Zhou Y [letter].
Diabetologia
; 58(9): 2193-4, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26113421
6.
The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach.
Mol Metab
; 21: 36-50, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30655217
7.
Genetic Nicotinamide N-Methyltransferase (Nnmt) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance.
Diabetes
; 68(3): 527-542, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30552109
8.
Peptide Optimization at the Drug Discovery-Development Interface: Tailoring of Physicochemical Properties Toward Specific Formulation Requirements.
J Pharm Sci
; 108(4): 1404-1414, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30528197
9.
Mass spectrometric detection of multiple extended series of neutral highly fucosylated N-acetyllactosamine oligosaccharides in human milk.
Int J Mass Spectrom
; 278(2-3): 129-136, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23538872
10.
Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice.
Cell Metab
; 28(2): 217-227.e13, 2018 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29937376
11.
Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
J Med Chem
; 61(13): 5580-5593, 2018 07 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29879354
12.
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders.
Sci Rep
; 8(1): 3660, 2018 02 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29483571
13.
Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.
Nat Med
; 23(6): 753-762, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28436957
14.
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
J Clin Invest
; 126(9): 3263-78, 2016 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27548521
15.
Comparative proteomic analysis of the rat spinal cord in inflammatory and neuropathic pain models.
Neurosci Lett
; 381(3): 289-93, 2005 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15896486
16.
Mice lacking neutral amino acid transporter B(0)AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control.
Mol Metab
; 4(5): 406-17, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25973388
17.
The calpain inhibitor MDL 28170 prevents inflammation-induced neurofilament light chain breakdown in the spinal cord and reduces thermal hyperalgesia.
Pain
; 110(1-2): 409-18, 2004 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15275793
18.
Structural analysis of underivatized neutral human milk oligosaccharides in the negative ion mode by nano-electrospray MS(n) (part 1: methodology).
J Am Soc Mass Spectrom
; 13(11): 1331-40, 2002 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12443024
19.
Structural analysis of underivatized neutral human milk oligosaccharides in the negative ion mode by nano-electrospray MS(n) (part 2: application to isomeric mixtures).
J Am Soc Mass Spectrom
; 13(11): 1341-8, 2002 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12443025
20.
Discovery and pharmacological characterization of SAR707 as novel and selective small molecule inhibitor of stearoyl-CoA desaturase (SCD1).
Eur J Pharmacol
; 707(1-3): 140-6, 2013 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-23524088