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1.
The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer.
Cancer Discov
; 4(6): 662-673, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24675041
2.
Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials.
J Med Chem
; 56(14): 5675-90, 2013 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-23742252
3.
Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist.
ACS Med Chem Lett
; 1(3): 130-4, 2010 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900187
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