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1.
Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer.
Commun Biol
; 7(1): 497, 2024 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38658677
2.
Human stem cell osteoblastogenesis mediated by novel glycogen synthase kinase 3 inhibitors induces bone formation and a unique bone turnover biomarker profile in rats.
Toxicol Appl Pharmacol
; 272(2): 399-407, 2013 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23872097
3.
Optimizing the Cell Painting assay for image-based profiling.
Nat Protoc
; 18(7): 1981-2013, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37344608
4.
AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kß/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors.
Oncogene
; 41(46): 5046-5060, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36241868
5.
Development of a quantitative 96-well method to image glycogen storage in primary rat hepatocytes.
Mol Cell Biochem
; 341(1-2): 73-8, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20333445
6.
A Novel Screening Approach for the Dissection of Cellular Regulatory Networks of NF-κB Using Arrayed CRISPR gRNA Libraries.
SLAS Discov
; 25(6): 618-633, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32476557
7.
Modeling Dose and Schedule Effects of AZD2811 Nanoparticles Targeting Aurora B Kinase for Treatment of Diffuse Large B-cell Lymphoma.
Mol Cancer Ther
; 18(5): 909-919, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30872381
8.
Characterization and Validation of a Human 3D Cardiac Microtissue for the Assessment of Changes in Cardiac Pathology.
Sci Rep
; 8(1): 10160, 2018 07 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29976997
9.
From the Cover: High-Throughput Imaging of Cardiac Microtissues for the Assessment of Cardiac Contraction during Drug Discovery.
Toxicol Sci
; 155(2): 444-457, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28069985
10.
Inhibiting PI3Kß with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors.
Clin Cancer Res
; 23(24): 7584-7595, 2017 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28972046
11.
Optimizing Therapeutic Effect of Aurora B Inhibition in Acute Myeloid Leukemia with AZD2811 Nanoparticles.
Mol Cancer Ther
; 16(6): 1031-1040, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28292940
12.
Immunofluorescence microscopy of SNAP23 in human skeletal muscle reveals colocalization with plasma membrane, lipid droplets, and mitochondria.
Physiol Rep
; 4(1)2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26733245
13.
Development and validation of a simple cell-based fluorescence assay for dipeptidyl peptidase 1 (DPP1) activity.
J Biomol Screen
; 16(1): 36-43, 2011 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21088147
14.
Glycogen synthase kinase-3α/ß inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage.
J Bone Miner Res
; 26(4): 811-21, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20939016
15.
Investigations into the liver effects of ximelagatran using high content screening of primary human hepatocyte cultures.
Expert Opin Drug Saf
; 7(4): 351-65, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18613800
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