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1.
New 'chemical probes' to examine the role of the hFPRL1 (or ALXR) receptor in inflammation.
Bioorg Med Chem Lett
; 17(23): 6633-7, 2007 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17920884
2.
Applications of parallel synthetic lead hopping and pharmacophore-based virtual screening in the discovery of efficient glycine receptor potentiators.
Eur J Med Chem
; 137: 63-75, 2017 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28575722
3.
Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators.
Nat Struct Mol Biol
; 24(2): 108-113, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27991902
4.
The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine Receptors.
J Med Chem
; 60(3): 1105-1125, 2017 02 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28001399
5.
Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitors.
J Med Chem
; 53(17): 6398-411, 2010 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-20712346
6.
Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase.
J Med Chem
; 53(7): 2973-85, 2010 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-20218619
7.
3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase.
J Med Chem
; 51(20): 6280-92, 2008 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-18817364
8.
Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold.
J Med Chem
; 51(20): 6271-9, 2008 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-18817365
9.
Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents.
Bioorg Med Chem Lett
; 16(14): 3713-8, 2006 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16697190
10.
Crystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetes.
Biochemistry
; 44(18): 6948-57, 2005 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-15865440
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