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1.
L-Asparaginase Conjugates from the Hyperthermophilic Archaea Thermococcus sibiricus with Improved Biocatalytic Properties.
Int J Mol Sci
; 25(8)2024 Apr 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38673759
2.
FTIR-based L-asparaginase activity assay enables continuous measurements in optically dense media including blood plasma.
Anal Biochem
; 598: 113694, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32217095
3.
Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes.
Biochem Biophys Res Commun
; 509(3): 790-796, 2019 02 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30612734
4.
Murine regulatory T cells induce death of effector T, B, and NK lymphocytes through a contact-independent mechanism involving telomerase suppression and telomere-associated senescence.
Cell Immunol
; 331: 146-160, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29935763
5.
Rhodospirillum rubruml-asparaginase targets tumor growth by a dual mechanism involving telomerase inhibition.
Biochem Biophys Res Commun
; 492(2): 282-288, 2017 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-28837806
6.
Comparative immunogenicity and structural analysis of epitopes of different bacterial L-asparaginases.
BMC Cancer
; 16: 89, 2016 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26867931
7.
Molecular Analysis of L-Asparaginases for Clarification of the Mechanism of Action and Optimization of Pharmacological Functions.
Pharmaceutics
; 14(3)2022 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35335974
8.
Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from Rhodospirillum rubrum by Conjugation with Chitosan-Based Cationic Polyelectrolytes.
Pharmaceuticals (Basel)
; 15(4)2022 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35455403
9.
Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
J Med Chem
; 64(15): 11432-11444, 2021 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34283610
10.
Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes.
Biochimie
; 174: 34-43, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32315661
11.
Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from Rhodospirillum rubrum to Inhibit Telomerase.
Pharmaceuticals (Basel)
; 13(10)2020 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33008089
12.
Endonuclease G modulates the alternative splicing of deoxyribonuclease 1 mRNA in human CD4+ T lymphocytes and prevents the progression of apoptosis.
Biochimie
; 157: 158-176, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30521874
13.
Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis.
Mol Immunol
; 101: 229-244, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30025223
14.
Alternative splicing of telomerase catalytic subunit hTERT generated by apoptotic endonuclease EndoG induces human CD4+ T cell death.
Eur J Cell Biol
; 96(7): 653-664, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28886883
15.
Inhibition of telomerase activity and induction of apoptosis by Rhodospirillum rubrum L-asparaginase in cancer Jurkat cell line and normal human CD4+ T lymphocytes.
Cancer Med
; 6(11): 2697-2712, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28984046
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