Detalles de la búsqueda
1.
BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors.
Mol Cancer
; 22(1): 110, 2023 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37443114
2.
Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL.
Blood
; 130(3): 310-322, 2017 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28202458
3.
Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells.
J Cell Physiol
; 228(8): 1651-7, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23460038
4.
Targeting BCL2 Overcomes Resistance and Augments Response to Aurora Kinase B Inhibition by AZD2811 in Small Cell Lung Cancer.
Clin Cancer Res
; 29(16): 3237-3249, 2023 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37289191
5.
The cooperation of FGF receptor and Klotho is involved in excretory canal development and regulation of metabolic homeostasis in Caenorhabditis elegans.
J Biol Chem
; 286(7): 5657-66, 2011 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-21177529
6.
Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors.
Nat Commun
; 13(1): 6021, 2022 10 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36224199
7.
Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance.
Clin Cancer Res
; 28(20): 4536-4550, 2022 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35921524
8.
N-Glycosylation regulates fibroblast growth factor receptor/EGL-15 activity in Caenorhabditis elegans in vivo.
J Biol Chem
; 284(48): 33030-9, 2009 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-19801543
9.
Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in Brca2-mutant mammary tumours.
Oncotarget
; 10(27): 2586-2606, 2019 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31080552
10.
Combined Inhibition of PI3Kß and mTOR Inhibits Growth of PTEN-null Tumors.
Mol Cancer Ther
; 17(11): 2309-2319, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30097489
11.
Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor-positive Breast Cancer.
Mol Cancer Ther
; 17(5): 908-920, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29483206
12.
The use of 18F-Fluoro-deoxy-glucose positron emission tomography (18F-FDG PET) as a non-invasive pharmacodynamic biomarker to determine the minimally pharmacologically active dose of AZD8835, a novel PI3Kα inhibitor.
PLoS One
; 12(8): e0183048, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28806782
13.
Inhibiting PI3Kß with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors.
Clin Cancer Res
; 23(24): 7584-7595, 2017 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28972046
14.
The use of (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) as a pathway-specific biomarker with AZD8186, a PI3Kß/δ inhibitor.
EJNMMI Res
; 6(1): 62, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27515445
15.
Intermittent High-Dose Scheduling of AZD8835, a Novel Selective Inhibitor of PI3Kα and PI3Kδ, Demonstrates Treatment Strategies for PIK3CA-Dependent Breast Cancers.
Mol Cancer Ther
; 15(5): 877-89, 2016 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26839307
16.
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo.
Sci Transl Med
; 8(325): 325ra17, 2016 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26865565
17.
AKT Antagonist AZD5363 Influences Estrogen Receptor Function in Endocrine-Resistant Breast Cancer and Synergizes with Fulvestrant (ICI182780) In Vivo.
Mol Cancer Ther
; 14(9): 2035-48, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26116361
18.
AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules.
Mol Cancer Ther
; 14(11): 2508-18, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26358751
19.
Carcinoma-associated fibroblasts are a promising therapeutic target.
Cancers (Basel)
; 5(1): 149-69, 2013 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-24216702
20.
Emerging roles of the tumor-associated stroma in promoting tumor metastasis.
Cell Adh Migr
; 6(3): 193-202, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22568980