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1.
The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness.
Nat Immunol
; 19(12): 1352-1365, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30420626
2.
Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome.
Bioorg Med Chem Lett
; 29(12): 1454-1458, 2019 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31005442
3.
Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome.
Bioorg Med Chem Lett
; 29(6): 821-825, 2019 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30691925
4.
Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors.
Bioorg Med Chem Lett
; 29(20): 126675, 2019 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31521475
5.
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.
Nat Chem Biol
; 11(3): 189-91, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25622091
6.
Corrigendum to 'Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors' [Bioorg. Med. Chem. Lett. 29 (2019) 126675].
Bioorg Med Chem Lett
; 30(2): 126771, 2020 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31859161
7.
Discovery of novel irreversible inhibitors of interleukin (IL)-2-inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket.
J Biol Chem
; 288(39): 28195-206, 2013 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-23935099
8.
Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function.
BMC Biochem
; 10: 11, 2009 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-19386136
9.
Proteolysis of prion protein by cathepsin S generates a soluble beta-structured intermediate oligomeric form, with potential implications for neurotoxic mechanisms.
Eur Biophys J
; 38(2): 209-18, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18813919
10.
Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome.
Acta Crystallogr F Struct Biol Commun
; 75(Pt 5): 385-391, 2019 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31045568
11.
Misfolded forms of glyceraldehyde-3-phosphate dehydrogenase interact with GroEL and inhibit chaperonin-assisted folding of the wild-type enzyme.
Protein Sci
; 14(4): 921-8, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15741339
12.
Identification of novel interacting partners of Sirtuin6.
PLoS One
; 7(12): e51555, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23240041
13.
Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses.
PLoS One
; 7(7): e39847, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22792191
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