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1.
Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy.
Am J Hum Genet
; 98(4): 735-43, 2016 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27058446
2.
Effects of M1 and M4 activation on excitatory synaptic transmission in CA1.
Hippocampus
; 27(7): 794-810, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28422371
3.
Inositol Phosphate Accumulation in Vivo Provides a Measure of Muscarinic M1 Receptor Activation.
Biochemistry
; 55(51): 7073-7085, 2016 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27958713
4.
Meta-analysis of amantadine efficacy for improving preclinical research reliability.
Mov Disord
; 33(10): 1555-1557, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30288778
5.
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
J Biol Chem
; 286(33): 28867-28875, 2011 Aug 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-21700703
6.
Muscarinic Acetylcholine Receptor Agonists as Novel Treatments for Schizophrenia.
Am J Psychiatry
; 179(9): 611-627, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35758639
7.
Effects of CYP46A1 Inhibition on Long-Term-Depression in Hippocampal Slices ex vivo and 24S-Hydroxycholesterol Levels in Mice in vivo.
Front Mol Neurosci
; 13: 568641, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33192294
8.
D1 Agonist Improved Movement of Parkinsonian Nonhuman Primates with Limited Dyskinesia Side Effects.
ACS Chem Neurosci
; 11(4): 560-566, 2020 02 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31971364
9.
In Vivo Modulation of Hippocampal Excitability by M4 Muscarinic Acetylcholine Receptor Activator: Implications for Treatment of Alzheimer's Disease and Schizophrenic Patients.
ACS Chem Neurosci
; 10(3): 1091-1098, 2019 03 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30335349
10.
Striatal, Hippocampal, and Cortical Networks Are Differentially Responsive to the M4- and M1-Muscarinic Acetylcholine Receptor Mediated Effects of Xanomeline.
ACS Chem Neurosci
; 10(3): 1753-1764, 2019 03 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30480428
11.
Discovery of Selective M4 Muscarinic Acetylcholine Receptor Agonists with Novel Carbamate Isosteres.
ACS Med Chem Lett
; 10(6): 941-948, 2019 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31223452
12.
ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities.
J Pharmacol Exp Ther
; 327(3): 827-39, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18753411
13.
The identification of neurotensin NTS1 receptor partial agonists through a ligand-based virtual screening approach.
Bioorg Med Chem Lett
; 18(21): 5789-91, 2008 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18849166
14.
Lack of Effect of Sodium Benzoate at Reported Clinical Therapeutic Concentration on d-Alanine Metabolism in Dogs.
ACS Chem Neurosci
; 9(11): 2832-2837, 2018 11 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-29893546
15.
Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity.
J Med Chem
; 60(15): 6649-6663, 2017 08 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28598634
16.
Oral administration of D-alanine in monkeys robustly increases plasma and cerebrospinal fluid levels but experimental D-amino acid oxidase inhibitors had minimal effect.
J Psychopharmacol
; 30(9): 887-95, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27287825
17.
Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects.
J Med Chem
; 59(13): 6313-28, 2016 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27275946
18.
Striatal, Hippocampal, and Cortical Networks Are Differentially Responsive to the M4- and M1-Muscarinic Acetylcholine Receptor Mediated Effects of Xanomeline.
ACS Chem Neurosci
; 10(8): 3910, 2019 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31286767
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