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1.
Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology.
J Biol Chem
; 295(52): 17935-17949, 2020 12 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32900849
2.
Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability.
J Med Chem
; 63(8): 3915-3934, 2020 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32212728
3.
Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase.
Cell Chem Biol
; 25(3): 309-317.e4, 2018 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29358052
4.
Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib.
PLoS One
; 13(4): e0195956, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29684045
5.
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun
; 14(1): 5019, 2023 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37596290
6.
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun
; 9(1): 1107, 2018 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29549331
7.
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun
; 9(1): 2071, 2018 05 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-29789663
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