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1.
Pharmacodynamics, pharmacokinetics, safety and tolerability of the novel dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 agonist RG7697 after single subcutaneous administration in healthy subjects.
Diabetes Obes Metab
; 19(10): 1446-1453, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28741871
2.
Pharmacodynamics, pharmacokinetics and safety of multiple ascending doses of the novel dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 agonist RG7697 in people with type 2 diabetes mellitus.
Diabetes Obes Metab
; 19(10): 1436-1445, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28730694
3.
Clinical pharmacology of emicizumab for the treatment of hemophilia A.
Expert Rev Clin Pharmacol
; 16(9): 775-790, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37529848
4.
Development of a population pharmacokinetic model to characterize the pharmacokinetics of intrathecally administered tominersen in cerebrospinal fluid and plasma.
CPT Pharmacometrics Syst Pharmacol
; 12(9): 1213-1226, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37221972
5.
A Phase I Study to Assess the Effect of Speed of Injection on Pain, Tolerability, and Pharmacokinetics After High-volume Subcutaneous Administration of Gantenerumab in Healthy Volunteers.
Clin Ther
; 42(1): 108-120.e1, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31883703
6.
Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Tofogliflozin (A SELECTIVE SGLT2 Inhibitor) in Patients with Type 2 Diabetes Mellitus.
Drug Res (Stuttg)
; 69(6): 314-322, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30103216
7.
Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study.
Lancet Haematol
; 6(6): e295-e305, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-31003963
8.
Oral administration of the 11ß-hydroxysteroid-dehydrogenase type 1 inhibitor RO5093151 to patients with glaucoma: an adaptive, randomised, placebo-controlled clinical study.
BMJ Open Ophthalmol
; 1(1): e000063, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29354707
9.
A novel double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [14C]tofogliflozin after oral administration and concomitant intravenous microdose administration of [13C]tofogliflozin in humans.
Clin Pharmacokinet
; 52(6): 463-73, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23494983
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