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1.
Continued Tumor Reduction of Metastatic Pheochromocytoma/Paraganglioma Harboring Succinate Dehydrogenase Subunit B Mutations with Cyclical Chemotherapy.
Cell Mol Neurobiol
; 38(5): 1099-1106, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29623478
2.
Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins.
Proc Natl Acad Sci U S A
; 112(5): 1571-6, 2015 Feb 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25605897
3.
Phase II Clinical Trial of Ixabepilone in Metastatic Cervical Carcinoma.
Oncologist
; 20(7): 725-6, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26040622
4.
Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole.
BMC Cancer
; 10: 143, 2010 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20398289
5.
Evidence for microtubule target engagement in tumors of patients receiving ixabepilone.
Clin Cancer Res
; 13(24): 7480-6, 2007 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18094432
6.
Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes.
Oncotarget
; 8(6): 9189-9199, 2017 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27999204
7.
Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer.
J Clin Oncol
; 23(12): 2726-34, 2005 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-15837987
8.
HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
Cancer Res
; 63(8): 1838-45, 2003 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12702571
9.
Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulin.
Mol Cancer Ther
; 3(10): 1319-27, 2004 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-15486199
10.
Microtubule-disrupting chemotherapeutics result in enhanced proteasome-mediated degradation and disappearance of tubulin in neural cells.
Cancer Res
; 70(14): 5870-9, 2010 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20587529
11.
A phase II clinical trial of ixabepilone (Ixempra; BMS-247550; NSC 710428), an epothilone B analog, in patients with metastatic renal cell carcinoma.
Clin Cancer Res
; 16(5): 1634-41, 2010 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20179242
12.
Proteasome inhibitors increase tubulin polymerization and stabilization in tissue culture cells: a possible mechanism contributing to peripheral neuropathy and cellular toxicity following proteasome inhibition.
Cell Cycle
; 7(7): 940-9, 2008 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18414063
13.
Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability.
Biochemistry
; 43(44): 13944-54, 2004 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-15518543
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